Protein Alignment TyrR and ser-5

DIOPT Version :9

• Sequence 1: NP_001287381.1
• Gene: TyrR / 42136
• FlyBaseID: FBgn0038542
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_492273.2
• Gene: ser-5 / 184572
• WormBaseID: WBGene00008890
• Length: 454
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 115/499 - (23%)
• Similarity: 177/499 - (35%)
• Gaps: 198/499 - (39%)

  Fly   117 IILIAVFATFIV-VTVIGNTLVILAILTTRRLRTITNCFVMSLAVADLLVGIFVMPPAVAVHLI- 179
            ::|:.:.|..|: :|:.||.||:  ....|..||.|...|.:|.:.|.|||:.|:|.. ||:||
 Worm    62 LVLLCIPAVIIILLTIFGNLLVL--FFKARVGRTNTTLLVWNLGLTDFLVGVIVLPMG-AVYLIY 123

  Fly   180 GSWQLGWVLCDIWISLDVLLCTASILSLCAISVDRYLAVTRPLTYSRKRRSKRLALIMILIVWLL 244
            ..|..|..||.:|::.||..||.|::::|.|||||||||||||.| :...:|...:.::.|:|:.
 Worm   124 RKWIFGRFLCRLWVAADVTFCTCSVVTICVISVDRYLAVTRPLRY-KSIVTKTKVISVMTIIWIF 187

  Fly   245 ALAITCPPMLGWYEPGRRDLRECRYNQNEGYVIFSAMGSFFIPMAVMIYVYARISCVIASRHDNM 309
            :.:|.. ..:.|.:|...|...|.......::..|.:.:||:|.:|.:.:|.||
 Worm   188 SSSILL-TTVRWEQPECYDDSLCFVGNEIRHLAHSVVFAFFLPASVTLTLYWRI----------- 240

  Fly   310 TDISVHNKKFKRYTAADVENELSEQEQHSSVGQRQRQ-ATSRTFSNQTIAKELQDMMLSDSDNCA 373
                        |..|                 |.|| |..|.|           :|:
 Worm   241 ------------YKLA-----------------RNRQKALDRGF-----------LMI------- 258

  Fly   374 AMGAGGAGGGGGGASSATGGTHCQSLLALPSGGVGGSMGCAKNGCYELTRPSSLKRASTASTTIT 438
                                                                             
 Worm   259 ----------------------------------------------------------------- 258

  Fly   439 TMTSGMGPGSSLLDAQWQSQPPGQTGQVQTHSLSQPP--RTHSFRHSHG--ERDRERLRSHHHHP 499
                 :|...:.|                |::|||..  |.| |..::|  |..|..||:|
 Worm   259 -----LGSNMNFL----------------TNTLSQQTTLRVH-FGKTNGMVEHQRRVLRTH---- 297

  Fly   500 HYHHQAGVTTTSTSGNTSANTNSKSLSNRITSLKKENKTTQTLSIVVGGFIACWLPFFINYLITP 564
                                                .:..:||.:|...|:.||||||..|| |.
 Worm   298 ------------------------------------ERIAKTLGVVSCSFLFCWLPFFGLYL-TN 325

  Fly   565 FLAEHQASQMLAKALTWLGWFNSAINPFIYAFYSVDFRAAFWRL 608
            :........:.....:|||:.||.:||.||:|...:|:.:.:||
 Worm   326 YKCSGCVPPIAIDVASWLGYCNSMLNPIIYSFTVKEFKRSAFRL 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrR	NP_001287381.1	7tm_4	127..>249	CDD:304433	50/123 (41%)
		7tm_1	133..>298	CDD:278431	59/165 (36%)
ser-5	NP_492273.2	7tmA_amine_R-like	64..365	CDD:320098	113/491 (23%)
		TM helix 1	65..87	CDD:320098	7/23 (30%)
		TM helix 2	96..118	CDD:320098	8/22 (36%)
		TM helix 3	134..156	CDD:320098	8/21 (38%)
		TM helix 4	179..195	CDD:320098	3/16 (19%)
		TM helix 5	215..238	CDD:320098	5/22 (23%)
		TM helix 6	298..323	CDD:320098	10/24 (42%)
		TM helix 7	334..359	CDD:320098	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010