Protein Alignment TyrR and DRD3

DIOPT Version :9

• Sequence 1: NP_001287381.1
• Gene: TyrR / 42136
• FlyBaseID: FBgn0038542
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_000787.2
• Gene: DRD3 / 1814
• HGNCID: 3024
• Length: 400
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 156/521 - (29%)
• Similarity: 223/521 - (42%)
• Gaps: 145/521 - (27%)

  Fly    96 NESAAAAEWAHFYDLVLSWQGIILIAVFATFIVVTVIGNTLVILAILTTRRLRTITNCFVMSLAV 160
            |.:.|:....|.| ..||:..:||..||         ||.||.:|:|..|.|:|.||..|:||||
Human    19 NSTGASQARPHAY-YALSYCALILAIVF---------GNGLVCMAVLKERALQTTTNYLVVSLAV 73

  Fly   161 ADLLVGIFVMPPAVAVHLIGS-WQLGWVLCDIWISLDVLLCTASILSLCAISVDRYLAVTRPLTY 224
            |||||...|||..|.:.:.|. |....:.||::::|||::||||||:|||||:|||.||..|:.|
Human    74 ADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHY 138

  Fly   225 SR---KRRSKRLALIMILIVWLLALAITCPPMLGWYEPGRRDLRECRYNQNEGYVIFSAMGSFFI 286
            ..   :...:|:|| ||..||:||.|::||.:.|:...|  |...|..: |..:||:|::.||::
Human   139 QHGTGQSSCRRVAL-MITAVWVLAFAVSCPLLFGFNTTG--DPTVCSIS-NPDFVIYSSVVSFYL 199

  Fly   287 PMAVMIYVYARISCVIASRHDNMTDISVHNKKFKRYTAADVENELSEQEQHSSVGQRQRQATSRT 351
            |..|.:.|||||..|:..|            :.||.        |:.|..       |..:....
Human   200 PFGVTVLVYARIYVVLKQR------------RRKRI--------LTRQNS-------QCNSVRPG 237

  Fly   352 FSNQTIAKELQDMMLSDSDN-CAAMGAGGAGGGGGGASSATGGTHCQSLLALPSGGVGGSMGCAK 415
            |..||::.:...:.|....: |.....||.|      ....||
Human   238 FPQQTLSPDPAHLELKRYYSICQDTALGGPG------FQERGG---------------------- 274

  Fly   416 NGCYELTRPSSLKRASTASTTITTMTSGMGPGSSLLDAQWQSQPPGQTGQVQTHSLSQPPRTHSF 480
                ||.|..  |..::.|.||....|                       ::...||
Human   275 ----ELKREE--KTRNSLSPTIAPKLS-----------------------LEVRKLS-------- 302

  Fly   481 RHSHGERDRERLRSHHHHPHYHHQAGVTTTSTSGNTSANTNSKSLSNRITSLKKENKTTQTLSIV 545
                                            :|..|.:.....|..|...| :|.|.||.::||
Human   303 --------------------------------NGRLSTSLKLGPLQPRGVPL-REKKATQMVAIV 334

  Fly   546 VGGFIACWLPFFINYLITPFLAEHQASQMLAKALTWLGWFNSAINPFIYAFYSVDFRAAFWR-LT 609
            :|.||.||||||:.:::.........|..|..|.||||:.|||:||.||..::::||.||.: |:
Human   335 LGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILS 399

  Fly   610 C 610
            |
Human   400 C 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrR	NP_001287381.1	7tm_4	127..>249	CDD:304433	60/125 (48%)
		7tm_1	133..>298	CDD:278431	77/168 (46%)
DRD3	NP_000787.2	7tm_4	44..>216	CDD:304433	82/184 (45%)
		7tm_1	46..383	CDD:278431	138/465 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D189663at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920