Protein Alignment TyrR and LOC100330650

DIOPT Version :10

• Sequence 1: NP_650652.1
• Gene: TyrR / 42136
• FlyBaseID: FBgn0038542
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: XP_002663705.4
• Gene: LOC100330650 / 100330650
• -ID: -
• Length: 431
• Species: Danio rerio
• Alignment Length: 518
• Identity: 149/518 - (28%)
• Similarity: 236/518 - (45%)
• Gaps: 133/518 - (25%)

  Fly   119 LIAVFA---TFIVV-TVIGNTLVILAILTTRRLRTITNCFVMSLAVADLLVGIFVMPPAVAVHLI 179
            :.||||   |.|:: |:.||.:||:|:||.|.||...|.|::|||.||:||...|:|.::|..|:
Zfish    17 ITAVFAITMTLIMLFTIFGNIMVIIAVLTCRSLRGPQNLFLVSLAAADILVATLVIPFSLAKELM 81

  Fly   180 GSWQLGWVLCDIWISLDVLLCTASILSLCAISVDRYLAVTRPLTYSRKRRSKRLALIMILIVWLL 244
            |.|....:.|:|.::||||.||:||:.|||||:||||:::||:.|..:|..:::. ..|::|||:
Zfish    82 GCWYFESLWCEIILALDVLFCTSSIIHLCAISLDRYLSISRPVQYGTQRTPRKIK-GAIVVVWLI 145

  Fly   245 ALAITCPPMLGWYEP--GRRDLR-ECRYNQNEGYVIFSAMGSFFIPMAVMIYVYARISCVIASRH 306
            :..|:.||::...:|  .:.|.| .|..|:::.|:::|.:||||.|..:||.||.|| ..||.:|
Zfish   146 SAIISFPPLVSMDKPQQAKGDPRTTCELNEDKWYILYSTIGSFFAPCLIMILVYVRI-YQIAKKH 209

  Fly   307 DNMTDISVHNKKFKRYTAADVENELSEQEQHSSVGQRQRQATSRTFSNQTIAKELQDMMLSDSDN 371
            .....                    .|..:.|:||                 :|||:
Zfish   210 TRCPP--------------------GEPRKDSTVG-----------------RELQN-------- 229

  Fly   372 CAAMGAGGAGGGGGGASSATGGTHCQS---------LLALPSGGVGGSMGCAKNGCYELTRPSSL 427
                      |..||..||.......|         ::...:.....|..|.:|
Zfish   230 ----------GKDGGVDSANNPNIAPSKSEAVKQPPVITESAQKTKRSRRCKEN----------- 273

  Fly   428 KRASTASTTITTMTSG---MGPGSSLLDAQWQSQPPGQTGQVQTHSLSQPPRTHSFRHSHGERDR 489
            |..|::|.:...:..|   .|..|::...:..::.|.|              :.|:|:
Zfish   274 KEESSSSGSDVEVVGGHDANGTNSNMASLETVNKTPAQ--------------SQSYRN------- 317

  Fly   490 ERLRSHHHHPHYHHQAGVTTTSTSGNTSANTNSKSLSN--RITSLKKENKTTQTLSIVVGGFIAC 552
                             :..|| .|:..||..:....|  |...:.:|.:.|..|::|:|.||.|
Zfish   318 -----------------IIATS-KGSQLANAKATGTPNTRRKAMIVREKRFTFVLAVVIGVFIIC 364

  Fly   553 WLPFFINY---LITPFLAEHQASQMLAKALTWLGWFNSAINPFIYAFYSVDFRAAFWRLTCKR 612
            |.|||.:|   .|.|.:.  :..:.|.....|:|:.|||:||.||..::.|||.||.::.|||
Zfish   365 WFPFFFSYSLQAICPDMC--KVPEGLFTFFFWIGYCNSALNPLIYTIFNRDFRKAFKKILCKR 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrR	NP_650652.1	7tmA_tyramine_R-like	118..>304	CDD:320189	81/191 (42%)
		TM helix 1	118..144	CDD:320189	13/28 (46%)
		TM helix 2	151..177	CDD:320189	12/25 (48%)
		TM helix 3	189..219	CDD:320189	19/29 (66%)
		TM helix 4	232..255	CDD:320189	7/22 (32%)
		TM helix 5	272..297	CDD:320189	11/24 (46%)
		7tm_GPCRs	<533..605	CDD:475119	28/74 (38%)
		TM helix 6	539..561	CDD:320189	12/24 (50%)
		TM helix 7	573..598	CDD:320189	10/24 (42%)
LOC100330650	XP_002663705.4	None