Protein Alignment TyrR and taar13d

DIOPT Version :10

• Sequence 1: NP_650652.1
• Gene: TyrR / 42136
• FlyBaseID: FBgn0038542
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_001076510.1
• Gene: taar13d / 100034379
• ZFINID: ZDB-GENE-041014-62
• Length: 341
• Species: Danio rerio
• Alignment Length: 525
• Identity: 113/525 - (21%)
• Similarity: 172/525 - (32%)
• Gaps: 246/525 - (46%)

  Fly   112 LSWQGIILIAVFATFIVVTVIGNTLVILAILTTRRLRTITNCFVMSLAVADLLVGIFVMPPAVAV 176
            :|.|.::.: :.|:.:.||::||::||::|...::|:|.||..|||||:||||:|:.|||.::..
Zfish    29 VSTQTVVYL-ILASAMTVTILGNSVVIISIAHFKQLQTTTNILVMSLALADLLLGLVVMPFSMIR 92

  Fly   177 HLIGSWQLGWVLCDIWISLDVLLCTASILSLCAISVDRYLAVTRPLTYSRKRRSKRLALIMILIV 241
            .:.|.|..|...|.:..|.|:.|.:.||..|..|:|||:.||..||.|.        .:|.|.:.
Zfish    93 SVDGCWYYGETFCMLHSSFDLFLTSVSIFHLIFIAVDRHQAVCFPLQYP--------TMITIPVA 149

  Fly   242 WLLALAITCPPMLGW-----YEPG-------RRDLRE----------CRYNQNEGYVIFSAMGSF 284
            |::.       |:.|     |..|       ...|.|          |....|..:.:...:.:|
Zfish   150 WVMV-------MISWSMAALYSYGLVYSKANMEGLDEYIQSMYCVGGCTLYFNALWSVLDTLITF 207

  Fly   285 FIPMAVMIYVYARISCVIASRHDNMTDISVHNKKFKRYTAADVENELSEQEQHSSVGQRQRQATS 349
            |:|.:|||.:|||| .|:|.:|                  |.:.||.::.|
Zfish   208 FLPCSVMIGLYARI-FVVAKKH------------------ARIINEANQNE-------------- 239

  Fly   350 RTFSNQTIAKELQDMMLSDSDNCAAMGAGGAGGGGGGASSATGGTHCQSLLALPSGGVGGSMGCA 414
                                                                             
Zfish   240 ----------------------------------------------------------------- 239

  Fly   415 KNGCYELTRPSSLKRASTASTTITTMTSGMGPGSSLLDAQWQSQPPGQTGQVQTHSLSQPPRTHS 479
                                                :|..::|
Zfish   240 ------------------------------------IDGTFKS---------------------- 246

  Fly   480 FRHSHGERDRERLRSHHHHPHYHHQAGVTTTSTSGNTSANTNSKSLSNRITSLKKENKTTQTLSI 544
                                                               |.:.|.|..:||.|
Zfish   247 ---------------------------------------------------SRRSEQKAAKTLGI 260

  Fly   545 VVGGFIACWLPFFINYLITPFLAEHQASQMLAKALTWLGWFNSAINPFIYAFYSVDFRAAFWRLT 609
            |||.||.||||||||.|:.|:: .......|.:|..|||:.||.:||.||.|:...||...:.:.
Zfish   261 VVGAFIMCWLPFFINSLMDPYI-NFSTPVALFEAFVWLGYINSTMNPIIYGFFYPWFRKTLYLII 324

  Fly   610 CKRFF 614
            .:|.|
Zfish   325 TRRIF 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrR	NP_650652.1	7tmA_tyramine_R-like	118..>304	CDD:320189	66/207 (32%)
		TM helix 1	118..144	CDD:320189	8/25 (32%)
		TM helix 2	151..177	CDD:320189	15/25 (60%)
		TM helix 3	189..219	CDD:320189	12/29 (41%)
		TM helix 4	232..255	CDD:320189	4/22 (18%)
		TM helix 5	272..297	CDD:320189	8/24 (33%)
		7tm_GPCRs	<533..605	CDD:475119	34/71 (48%)
		TM helix 6	539..561	CDD:320189	16/21 (76%)
		TM helix 7	573..598	CDD:320189	12/24 (50%)
taar13d	NP_001076510.1	7tmA_TAARs	33..320	CDD:320183	109/510 (21%)
		TM helix 1	34..60	CDD:320183	8/26 (31%)
		TM helix 2	67..93	CDD:320183	15/25 (60%)
		TM helix 3	105..135	CDD:320183	12/29 (41%)
		TM helix 4	147..170	CDD:320183	5/29 (17%)
		TM helix 5	195..224	CDD:320183	11/29 (38%)
		TM helix 6	249..279	CDD:320183	19/29 (66%)
		TM helix 7	288..313	CDD:320183	12/24 (50%)