Protein Alignment TyrRII and adra2a

DIOPT Version :9

• Sequence 1: NP_001262682.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001072843.1
• Gene: adra2a / 780304
• XenbaseID: XB-GENE-877030
• Length: 434
• Species: Xenopus tropicalis
• Alignment Length: 514
• Identity: 143/514 - (27%)
• Similarity: 222/514 - (43%)
• Gaps: 143/514 - (27%)

  Fly    73 PKSLAVAVFLV-----IILVTVVGNTLVILAVLTTRRLRTVTNCFVMNLAITDWLVGTCVMPPSV 132
            |.||.|.:.|:     ::|.||.||.|||:||.|:|.|:...|.|:::||..|.||.|.|:|.|:
 Frog    40 PYSLEVTLALITLVGMLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSL 104

  Fly   133 VLYITGTWRFGWILCDIWISLDILLCSGSILSLCAISLDRYLAVTQPLTYSKKRRSKRLALLMIL 197
            ...:.|.|.||.:.|:|:::||:|.|:.||:.|||||||||.::||.:.|:.||..:|:..: |.
 Frog   105 SNEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKCI-IF 168

  Fly   198 VVWITALSITCPPYLGWYEVGRHQAEFVDCRYNQNKGYVVFSAMGSFFIPLTVMLYVYVKIGYVL 262
            :||:.:..|:.||.: ..|....:.|...|:.|..|.|:::|::||||.|..:|:.||::| |.:
 Frog   169 IVWVISAVISFPPLI-TIEKESGKVEMPICKINDEKWYIIYSSIGSFFAPCVIMVLVYIRI-YQI 231

  Fly   263 TSRRQRIVRDAYSERTADYDVDGDNFISESEHYHCTPTKWLPNRKSRWRFNSLHDPPPSAATNAA 327
            ..:|.|:                                                 ||...:|||
 Frog   232 AKKRTRV-------------------------------------------------PPGKRSNAA 247

  Fly   328 ---AKGHQSSVKCSKCSKCSSATGTAGAGAGAGVVDKTLTFKHQPTFYELVEVSRLSSLIHCSAI 389
               ||.|.                        |:.:|.|..|..
 Frog   248 EVGAKQHN------------------------GLAEKDLPVKLN--------------------- 267

  Fly   390 SCKYGGPCMHSTPSGMHYVGTEASFSDTCLGGNVSNNTTTTTTNTVALETNEKLEAEAKQKQQ-- 452
            ..|.||      ..|.|....||:      |.::.:::::        |..|..:.:|::||.
 Frog   268 GDKAGG------SGGDHGKEVEAN------GVDMDDSSSS--------EHQEDNQYQARKKQDKL 312

  Fly   453 ---QQRSSFDHHHPHAHHHGSHGQQSHHNHHHRMPMRVSTTK----RDSKTAKTLTIVMGGLIAC 510
               :.::......|        |.........|.| :||..|    |:.:....|.:|:|..:.|
 Frog   313 PRGKGKTKLSQIKP--------GDSLPRREEERNP-KVSRWKGRQNREKRFTFVLAVVIGVFVIC 368

  Fly   511 WLPFFVYYLLIPFLPRPAVLEDLMFGFTWIGWVNCAINPFIYAFYNPDFRTAFWRLTCR 569
            |.|||..|.|:....|..|...|...|.|.|:.|.::|||||..:|.|||.||.::.|:
 Frog   369 WFPFFFTYTLMAVCVRCYVPAPLFKFFFWFGYCNSSLNPFIYTIFNHDFRRAFKKILCK 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_001262682.1	7tm_4	82..>212	CDD:304433	58/134 (43%)
		7tm_1	91..>277	CDD:278431	73/185 (39%)
adra2a	NP_001072843.1	7tmA_alpha2A_AR	47..421	CDD:320445	136/499 (27%)
		TM helix 1	48..74	CDD:320445	11/25 (44%)
		TM helix 2	81..107	CDD:320445	11/25 (44%)
		TM helix 3	119..149	CDD:320445	17/29 (59%)
		TM helix 4	161..184	CDD:320445	7/24 (29%)
		TM helix 5	202..231	CDD:320445	13/29 (45%)
		TM helix 6	349..379	CDD:320445	10/29 (34%)
		TM helix 7	389..414	CDD:320445	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000