Protein Alignment TyrRII and LOC563567

DIOPT Version :10

• Sequence 1: NP_650651.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_021330044.2
• Gene: LOC563567 / 563567
• -ID: -
• Length: 447
• Species: Danio rerio
• Alignment Length: 558
• Identity: 132/558 - (23%)
• Similarity: 202/558 - (36%)
• Gaps: 233/558 - (41%)

  Fly    17 LSTALTVASGNSNSSDGTLLLIQTSAAPGGDVMATGAGAGKLGVPSMNSYLVSMAWPKSLAVAVF 81
            :.|.|.:.:|.:::.|         .|.|......|.|...:               ::|...|.
Zfish     1 MDTILEMENGTNHTQD---------RAHGAQEREDGDGQNSV---------------RALLGFVL 41

  Fly    82 LVIILVTVVGNTLVILAVLTTRRLRT-VTNCFVMNLAITDWLVGTCVMPPSVVLYITGTWRFGWI 145
            .::|:.|::|||||..||:..|.||: |||.||::||::|..|...|||...:..:.|||.|| .
Zfish    42 FLLIVSTLLGNTLVCAAVVKFRHLRSKVTNFFVISLAVSDLFVAVLVMPWEAISAVAGTWLFG-R 105

  Fly   146 LCDIWISLDILLCSGSILSLCAISLDRYLAVTQPLTYSKKRRSKRLALLMILVVWITALSIT-CP 209
            .|.|||:.||:..:.|||:||.||:|||.|:..|..|.:| .:.|:|.:||.|.|..::.|: .|
Zfish   106 FCGIWIAFDIMCSTASILNLCIISVDRYWAIASPFRYERK-MTHRVAFMMIGVAWTLSILISFIP 169

  Fly   210 PYLGWY-------EVGRHQAEFVD-CRYNQNKGYVVFSAMGSFFIPLTVMLYVYVKIGYVLTSRR 266
            ..|.|:       ..|.:..::.| |:.|.|:.|.:.|::.||:||:.:|:..|.:|..:..::.
Zfish   170 VQLNWHMADDDEEGAGGNGTDYSDNCKANLNRTYAISSSLISFYIPVIIMIATYTRIFRIAQTQI 234

  Fly   267 QRIVRDAYSERTADYDVDGDNFISESEHYHCTPTKWLPNRKSRWRFNSLHDPPPSAATNAAAKGH 331
            :||   :..||..::                                              |:.|
Zfish   235 RRI---SSLERAVEH----------------------------------------------AQNH 250

  Fly   332 QSSVKCSKCSKCSSATGTAGAGAGAGVVDKTLTFKHQPTFYELVEVSRLSSLIHCSAISCKYGGP 396
            ..|..||
Zfish   251 HQSNDCS---------------------------------------------------------- 257

  Fly   397 CMHSTPSGMHYVGTEASFSDTCLGGNVSNNTTTTTTNTVALETNEKLEAEAKQKQQQQRSSFDHH 461
                                                |..:|:|
Zfish   258 ------------------------------------NENSLKT---------------------- 264

  Fly   462 HPHAHHHGSHGQQSHHNHHHRMPMRVSTTKRDSKTAKTLTIVMGGLIACWLPFFVYYLLIPFLPR 526
                                       |.|:::|..|||:|:||..:.|||||||...::||.
Zfish   265 ---------------------------TFKKETKVLKTLSIIMGVFVFCWLPFFVLNCMVPFC-- 300

  Fly   527 PAVLEDLMFG-FTWIGWVNCAINPFIYAFYNPDFRTAF 563
             ..:.|..|. |.|.||.|.::||.|||| |.|||.||
Zfish   301 -QCVSDTTFTIFVWFGWANSSLNPVIYAF-NADFRKAF 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_650651.1	7tm_GPCRs	78..>270	CDD:475119	75/201 (37%)
		TM helix 1	78..101	CDD:410628	10/22 (45%)
		TM helix 2	110..132	CDD:410628	10/21 (48%)
		TM helix 3	148..170	CDD:410628	11/21 (52%)
		TM helix 4	194..210	CDD:410628	5/16 (31%)
		TM helix 5	233..256	CDD:410628	7/22 (32%)
		7tm_GPCRs	<491..563	CDD:475119	34/72 (47%)
		TM helix 6	497..519	CDD:320098	13/21 (62%)
		TM helix 7	531..556	CDD:320098	13/25 (52%)
LOC563567	XP_021330044.2	None