Protein Alignment TyrRII and 5-HT2B

DIOPT Version :9

• Sequence 1: NP_001262682.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001262373.1
• Gene: 5-HT2B / 41017
• FlyBaseID: FBgn0261929
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 512
• Identity: 132/512 - (25%)
• Similarity: 210/512 - (41%)
• Gaps: 122/512 - (23%)

  Fly    25 SGNSNSSDGTLLLIQTSAAPGGDVMATGAGAGKLGVP-SMNSYLVSMAWPKSLAVAVFLVIILVT 88
            :.|:.|....|.:.:.:|.....:.||..     .|| ..|:|...:|          ||::|.|
  Fly    38 TANATSRHNQLHVARWNATGNATISATFE-----DVPFDANNYWALLA----------LVLVLGT 87

  Fly    89 VVGNTLVILAVLTTRRLRTVTNCFVMNLAITDWLVGTCVMPPSVVLYITGTWRFGWILCDIWISL 153
            ..||.||.||:...|||:.|||.|:|:|||||.:|...|||..::..:.|.:..|...|..||.|
  Fly    88 AAGNILVCLAIAWERRLQNVTNYFLMSLAITDLMVAVLVMPLGILTLVKGYFPLGSEHCLTWICL 152

  Fly   154 DILLCSGSILSLCAISLDRYLAVTQPLTYSKKRRSKRLALLMILVVWITALSITCPPYLGWYEVG 218
            |:|.|:.||:.||.||:||||::..|:.:.:.:..:|:. |.|:.||:.:::::.|
  Fly   153 DVLFCTASIMHLCTISVDRYLSLRYPMRFGRNKTRRRVT-LKIVFVWLLSIAMSLP--------- 207

  Fly   219 RHQAEFVDCRYNQNKGYV-----------VFSAMGS---FFIPLTVMLYVYVKIGYVLTSRRQRI 269
                  :...|::|...|           |:..:||   |:|||.|||..|.....:|..:||.:
  Fly   208 ------LSLMYSKNHASVLVNGTCQIPDPVYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQNL 266

  Fly   270 VRDAYSERTADYDVDGDNFISESEHYHCTP---TKWLP-----NRKSRWRFNSLHDPPPSAATNA 326
               ...::||                ..||   :.||.     .|:..||  .|..|.|.   ||
  Fly   267 ---GGGQQTA----------------AATPGWASGWLGQAPALERRCTWR--RLLKPGPG---NA 307

  Fly   327 AAKGHQSSVKCSKCSKCSSATGTAGAGAGAGVVDKTLTFKHQPTFYELVEVSRLSSLIHCSAISC 391
            ::..|..|         :::|.|          |.:....|:               :.....|.
  Fly   308 SSVLHAHS---------ANSTDT----------DLSTLDNHE---------------LWLPDSSI 338

  Fly   392 KYGGPCMHSTPSGMHYVGTEASFSDTCLGGNVSNNTT-TTTTNTVALETNEKLEAEAKQKQQQQR 455
            |...|   :|.:.:|..|.|.......|....|::|| :.|.:..:|..:.:|:..:..::....
  Fly   339 KEPTP---TTMTALHQFGAEMLKLSRGLESVASSSTTGSPTKSEFSLSNHLQLQYPSSPQRYAAT 400

  Fly   456 SSFDHHHPHAHHHGS--HGQQSHHNHHHRMPMRVSTT----KRDSKTAKTLTIVMGG 506
            ....|||.|..|...  |.|.|....|....:.:|||    :|:|......:..|||
  Fly   401 HQQSHHHNHQQHPAGVYHQQASPKGRHGTTVLGLSTTTLGIERESTRNSLASSRMGG 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_001262682.1	7tm_4	82..>212	CDD:304433	53/129 (41%)
		7tm_1	91..>277	CDD:278431	66/199 (33%)
5-HT2B	NP_001262373.1	7tm_1	90..>262	CDD:278431	64/187 (34%)
		7tm_4	90..>238	CDD:304433	54/163 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460678
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840