DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TyrRII and DopEcR

DIOPT Version :9

Sequence 1:	NP_001262682.1	Gene:	TyrRII / 42135	FlyBaseID:	FBgn0038541	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001014559.1	Gene:	DopEcR / 38539	FlyBaseID:	FBgn0035538	Length:	322	Species:	Drosophila melanogaster

Alignment Length:	151	Identity:	55/151 - (36%)
Similarity:	85/151 - (56%)	Gaps:	2/151 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 SYLVSMAWPKSLAVAVFLVIILVTVVGNTLVILAVLTTRRLRT-VTNCFVMNLAITDWLVGTCVM 128
            |||...:..::|..||.:.|:.|.:|.:.|:|:|.....:..| |.|.::::|||.|.|.|..|:
  Fly     5 SYLQDNSKVEALTKAVLISILGVAIVLSNLLIIATYANFKGPTEVINYYLLSLAIADLLCGLLVV 69

  Fly   129 PPSVVLYITGTWRFGWILCDIWISLDILLCSGSILSLCAISLDRYLAVTQPLTYSKKRRSKRLAL 193
            |.||...:||.|.:|.|:|.....|::.|.:.|:.:...||:||||||.:||.|...:...|...
  Fly    70 PFSVYPALTGEWMYGDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLRYETVQTKTRCQC 134

  Fly   194 LMILVVWITALSITCPPYLGW 214
            .|:. .||:|..:.|||.||:
  Fly   135 WMVF-TWISAALLCCPPILGY 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_001262682.1	7tm_4	82..>212	CDD:304433	47/130 (36%)
TyrRII	NP_001262682.1	7tm_1	91..>277	CDD:278431	46/125 (37%)
DopEcR	NP_001014559.1	7tm_classA_rhodopsin-like	18..289	CDD:410626	51/138 (37%)
		TM helix 1	18..42	CDD:410626	8/23 (35%)
		TM helix 2	51..73	CDD:410626	9/21 (43%)
		TM helix 3	89..111	CDD:410626	4/21 (19%)
		TM helix 4	134..150	CDD:410626	5/16 (31%)
		TM helix 5	174..197	CDD:410626
		TM helix 6	230..252	CDD:410626
		TM helix 7	264..289	CDD:410626
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460666
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940