Protein Alignment TyrRII and Adra1d

DIOPT Version :9

• Sequence 1: NP_001262682.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_077809.2
• Gene: Adra1d / 29413
• RGDID: 62064
• Length: 562
• Species: Rattus norvegicus
• Alignment Length: 552
• Identity: 139/552 - (25%)
• Similarity: 210/552 - (38%)
• Gaps: 194/552 - (35%)

  Fly    42 AAPGGDVMATGAG--------------AGKL-GVPSMNSYLVSMAWPKSLAVAVFL-VIILVTVV 90
            |..||.|:.||:|              :|:: |..::...:||   .:.:.|.||| ..||..|.
  Rat    45 ATGGGAVVGTGSGEDNQSSTGEPGAAASGEVNGSAAVGGLVVS---AQGVGVGVFLAAFILTAVA 106

  Fly    91 GNTLVILAVLTTRRLRTVTNCFVMNLAITDWLVGTCVMPPSVVLYITGTWRFGWILCDIWISLDI 155
            ||.||||:|...|.|:||||.|::|||:.|.|:...|:|.|..:.:.|.|.||...||:|.::|:
  Rat   107 GNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDV 171

  Fly   156 LLCSGSILSLCAISLDRYLAVTQPLTYSKKRRSKRLALLMILVVWITALSITCPPYLGWYEVGRH 220
            |.|:.||||||.||:|||:.|...|.|......::.|.::.| :|..||.::..|.|||.|....
  Rat   172 LCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILAL-LWAVALVVSVGPLLGWKEPVPP 235

  Fly   221 QAEFVDCRYNQNKGYVVFSAMGSFFIPLTVMLYVYVKIGYVLTSRRQRIVRDAYSERTADYDVDG 285
            ...|  |...:..||.:||::.||::|:.|::.:|.:: ||:
  Rat   236 DERF--CGITEEVGYAIFSSVCSFYLPMAVIVVMYCRV-YVV----------------------- 274

  Fly   286 DNFISESEHYHCTPTKWLPNRKSRWRFNSLHDPPPSAATNAAAKGHQSSVKCSKCSKCSSATGTA 350
                                                                     ..|.|.:.
  Rat   275 ---------------------------------------------------------ARSTTRSL 282

  Fly   351 GAGAGAGVVDKTLTFKHQPTFYELVEVSRLSSLIHCSAISCKYGGPCMHSTPSGMHYVGTEASFS 415
            .||           .|.:|.     :.|.:...|||..           :..|...|.||::|
  Rat   283 EAG-----------IKREPG-----KASEVVLRIHCRG-----------AATSAKGYPGTQSS-- 318

  Fly   416 DTCLGGNVSNNTTTTTTNTVALETNEKLEAEAKQKQQQQRSSFDHHHPHAHHHGSHGQQSHHNHH 480
                                              |....|||
  Rat   319 ----------------------------------KGHTLRSS----------------------- 326

  Fly   481 HRMPMRVSTTKRDSKTAKTLTIVMGGLIACWLPFFVYYLLIPFLPRPAVLEDLMFGFTWIGWVNC 545
              :.:|:....|:.|.||||.||:|..:.||.|||....|....|:....|.:.....|:|:.|.
  Rat   327 --LSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNS 389

  Fly   546 AINPFIYAFYNPDFRTAFWR-LTCRPICKQKR 576
            .:||.||...:.:|:.||.| |.|:  |:::|
  Rat   390 CVNPLIYPCSSREFKRAFLRLLRCQ--CRRRR 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_001262682.1	7tm_4	82..>212	CDD:304433	56/130 (43%)
		7tm_1	91..>277	CDD:278431	69/185 (37%)
Adra1d	NP_077809.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	10..71		7/25 (28%)
		7tm_GPCRs	91..407	CDD:421689	121/487 (25%)
		TM helix 1	92..118	CDD:410628	14/25 (56%)
		TM helix 2	125..151	CDD:410628	11/25 (44%)
		TM helix 3	163..193	CDD:410628	17/29 (59%)
		TM helix 4	205..228	CDD:410628	6/23 (26%)
		TM helix 5	245..274	CDD:410628	10/29 (34%)
		TM helix 6	335..365	CDD:410628	14/29 (48%)
		TM helix 7	375..400	CDD:410628	8/24 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	452..481

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	268	1.000	Inparanoid score	I2951
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960