Protein Alignment TyrRII and ser-5

DIOPT Version :9

• Sequence 1: NP_001262682.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_492273.2
• Gene: ser-5 / 184572
• WormBaseID: WBGene00008890
• Length: 454
• Species: Caenorhabditis elegans
• Alignment Length: 527
• Identity: 115/527 - (21%)
• Similarity: 181/527 - (34%)
• Gaps: 217/527 - (41%)

  Fly    77 AVAVFL-----VIILVTVVGNTLVILAVLTTRRLRTVTNCFVMNLAITDWLVGTCVMPPSVVLYI 136
            ||.|.|     :|||:|:.||.||:.  ...|..||.|...|.||.:||:|||..|:|...|..|
 Worm    60 AVLVLLCIPAVIIILLTIFGNLLVLF--FKARVGRTNTTLLVWNLGLTDFLVGVIVLPMGAVYLI 122

  Fly   137 TGTWRFGWILCDIWISLDILLCSGSILSLCAISLDRYLAVTQPLTYSKKRRSKRLALLMILVVWI 201
            ...|.||..||.:|::.|:..|:.|::::|.||:|||||||:||.| |...:|...:.::.::||
 Worm   123 YRKWIFGRFLCRLWVAADVTFCTCSVVTICVISVDRYLAVTRPLRY-KSIVTKTKVISVMTIIWI 186

  Fly   202 TALSITCPPYLGWYEVGRHQAEFVD---CRYNQNKGYVVFSAMGSFFIPLTVMLYVYVKIGYVLT 263
            .:.||.... :.|     .|.|..|   |.......::..|.:.:||:|.:|.|.:|.:| |.|.
 Worm   187 FSSSILLTT-VRW-----EQPECYDDSLCFVGNEIRHLAHSVVFAFFLPASVTLTLYWRI-YKLA 244

  Fly   264 SRRQRIVRDAYSERTADYDVDGDNFISESEHYHCTPTKWLPNRKSRWRFNSLHDPPPSAATNAAA 328
            ..||:.:...:
 Worm   245 RNRQKALDRGF------------------------------------------------------ 255

  Fly   329 KGHQSSVKCSKCSKCSSATGTAGAGAGAGVVDKTLTFKHQPTFYELVEVSRLSSLIHCSAISCKY 393
                                                                             
 Worm   256 ----------------------------------------------------------------- 255

  Fly   394 GGPCMHSTPSGMHYVGTEASFSDTCLGGNVSNNTTTTTTNTVALETNEKLEAEAKQKQQQQRSSF 458
                       :..:|:..:|                .|||::.:|..::
 Worm   256 -----------LMILGSNMNF----------------LTNTLSQQTTLRV--------------- 278

  Fly   459 DHHHPHAHHHGSHGQQSHHNHHHRMPMRVSTTKRDSKTAKTLTIVMGGLIACWLPFFVYYL---- 519
                   |...::|...|.....|...|:         ||||.:|....:.||||||..||
 Worm   279 -------HFGKTNGMVEHQRRVLRTHERI---------AKTLGVVSCSFLFCWLPFFGLYLTNYK 327

  Fly   520 ---LIPFLPRPAVLEDLMFGFTWIGWVNCAINPFIYAFYNPDF-RTAF------WRLTCRPICKQ 574
               .:|    |..::..    :|:|:.|..:||.||:|...:| |:||      |:...|.:...
 Worm   328 CSGCVP----PIAIDVA----SWLGYCNSMLNPIIYSFTVKEFKRSAFRLVVPIWQFVNRCLPFV 384

  Fly   575 KRPPNHL 581
            ..||:::
 Worm   385 PAPPDNI 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_001262682.1	7tm_4	82..>212	CDD:304433	53/134 (40%)
		7tm_1	91..>277	CDD:278431	65/188 (35%)
ser-5	NP_492273.2	7tmA_amine_R-like	64..365	CDD:320098	105/495 (21%)
		TM helix 1	65..87	CDD:320098	9/23 (39%)
		TM helix 2	96..118	CDD:320098	10/21 (48%)
		TM helix 3	134..156	CDD:320098	6/21 (29%)
		TM helix 4	179..195	CDD:320098	4/15 (27%)
		TM helix 5	215..238	CDD:320098	6/22 (27%)
		TM helix 6	298..323	CDD:320098	12/33 (36%)
		TM helix 7	334..359	CDD:320098	9/28 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010