Protein Alignment TyrRII and DRD3

DIOPT Version :9

• Sequence 1: NP_001262682.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_000787.2
• Gene: DRD3 / 1814
• HGNCID: 3024
• Length: 400
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 146/513 - (28%)
• Similarity: 218/513 - (42%)
• Gaps: 139/513 - (27%)

  Fly    64 NSYLVSMAWPKSLAVAVFLVIILVTVVGNTLVILAVLTTRRLRTVTNCFVMNLAITDWLVGTCVM 128
            ||...|.|.|.:.....:..:||..|.||.||.:|||..|.|:|.||..|::||:.|.||.|.||
Human    19 NSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVM 83

  Fly   129 PPSVVLYIT-GTWRFGWILCDIWISLDILLCSGSILSLCAISLDRYLAVTQPLTY--SKKRRSKR 190
            |..|.|.:| |.|.|..|.||::::||:::|:.|||:|||||:|||.||..|:.|  ...:.|.|
Human    84 PWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCR 148

  Fly   191 LALLMILVVWITALSITCPPYLGWYEVGRHQAEFVDCRYNQNKGYVVFSAMGSFFIPLTVMLYVY 255
            ...|||..||:.|.:::||...|:...|    :...|..: |..:|::|::.||::|..|.:.||
Human   149 RVALMITAVWVLAFAVSCPLLFGFNTTG----DPTVCSIS-NPDFVIYSSVVSFYLPFGVTVLVY 208

  Fly   256 VKIGYVLTSRRQRIVRDAYSERTADYDVDGDNFISESEHYHCTPTKWLPNRKSRWRFNSLHDPPP 320
            .:|..||..||:                                 |.:..|::
Human   209 ARIYVVLKQRRR---------------------------------KRILTRQN------------ 228

  Fly   321 SAATNAAAKGHQSSVKCSKCSKCSSATGTAGAGAGAGVVDKTLTFKHQPTFYELVEVSRLSSLIH 385
                                |:|:|..        .|...:||:  ..|...||   .|..|:..
Human   229 --------------------SQCNSVR--------PGFPQQTLS--PDPAHLEL---KRYYSICQ 260

  Fly   386 CSAISCKYGGPCMHSTPSGMHYVGTEASFSDTCLGGNVSNNTTTTTTNTVALE----TNEKLEAE 446
            .:|:    |||       |....|.|....:     ...|:.:.|....::||    :|.:|...
Human   261 DTAL----GGP-------GFQERGGELKREE-----KTRNSLSPTIAPKLSLEVRKLSNGRLSTS 309

  Fly   447 AKQKQQQQRSSFDHHHPHAHHHGSHGQQSHHNHHHRMPMRVSTTKRDSKTAKTLTIVMGGLIACW 511
            .|....|.|.                          :|:      |:.|..:.:.||:|..|.||
Human   310 LKLGPLQPRG--------------------------VPL------REKKATQMVAIVLGAFIVCW 342

  Fly   512 LPFFVYYLLIPFLPRPAVLEDLMFGFTWIGWVNCAINPFIYAFYNPDFRTAFWR-LTC 568
            ||||:.::|........|..:|....||:|:||.|:||.||..:|.:||.||.: |:|
Human   343 LPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_001262682.1	7tm_4	82..>212	CDD:304433	62/132 (47%)
		7tm_1	91..>277	CDD:278431	76/188 (40%)
DRD3	NP_000787.2	7tm_4	44..>216	CDD:304433	74/176 (42%)
		7tm_1	46..383	CDD:278431	129/467 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D189663at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920