Protein Alignment TyrRII and ADRA1B

DIOPT Version :9

• Sequence 1: NP_001262682.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_011532737.1
• Gene: ADRA1B / 147
• HGNCID: 278
• Length: 556
• Species: Homo sapiens
• Alignment Length: 561
• Identity: 141/561 - (25%)
• Similarity: 206/561 - (36%)
• Gaps: 227/561 - (40%)

  Fly    62 SMNSYLVSMAWPKSLAVAVFL-VIILVTVVGNTLVILAVLTTRRLRTVTNCFVMNLAITDWLVGT 125
            |.||.|..:...::::|.:.| ..||..:|||.||||:|...|.|||.||.|::|||:.|.|:..
Human    32 SSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSF 96

  Fly   126 CVMPPSVVLYITGTWRFGWILCDIWISLDILLCSGSILSLCAISLDRYLAVTQPLTYSKKRRSKR 190
            .|:|.|..|.:.|.|..|.|.||||.::|:|.|:.|||||||||:|||:.|...|.| ....::|
Human    97 TVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQY-PTLVTRR 160

  Fly   191 LALLMILVVWITALSITCPPYLGWYEVGRHQAEFVDCRYNQNKGYVVFSAMGSFFIPLTVMLYVY 255
            .|:|.:|.||:.:..|:..|.|||.|...:..:  :|...:...|.:||::|||:|||.|:|.:|
Human   161 KAILALLSVWVLSTVISIGPLLGWKEPAPNDDK--ECGVTEEPFYALFSSLGSFYIPLAVILVMY 223

  Fly   256 VKIGYVLTSRRQRIVRDAYSERTADYDVDGDNFISESEHYHCTPTKWLPNRKSRWRFNSLHDPPP 320
            .:: |::..|                                 .||.|.
Human   224 CRV-YIVAKR---------------------------------TTKNLE---------------- 238

  Fly   321 SAATNAAAKGHQSSVKCSKCSKCSSATGTAGAGAGAGVV-----DKTLTFK-HQPTFYELVEVSR 379
                                               |||:     .|.||.: |...|:|
Human   239 -----------------------------------AGVMKEMSNSKELTLRIHSKNFHE------ 262

  Fly   380 LSSLIHCSAISCKYGGPCMHSTPSGMHYVGTEASFSDTCLGGNVSNNTTTTTTNTVALETNEKLE 444
                                                          :|.::|
Human   263 ----------------------------------------------DTLSST------------- 268

  Fly   445 AEAKQKQQQQRSSFDHHHPHAHHHGSHGQQSHHNHHHRMPMRVSTTKRDSKTAKTLTIVMGGLIA 509
               |.|....|||                         :.:::....|:.|.||||.||:|..|.
Human   269 ---KAKGHNPRSS-------------------------IAVKLFKFSREKKAAKTLGIVVGMFIL 305

  Fly   510 CWLPFFVYYLLIPFLPRPAVLE-----------------------------------DLMFGFT- 538
            ||||||:...|.|..|.|..|.                                   |.:|...
Human   306 CWLPFFIALPLDPDSPPPTHLRVVPAPWGHSSIMNLPLVLPLDATRSGSLFSTLKPPDAVFKVVF 370

  Fly   539 WIGWVNCAINPFIYAFYNPDFRTAFWRL---TCRPICKQKR 576
            |:|:.|..:||.||...:.:|:.||.|:   .||...:::|
Human   371 WLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRR 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_001262682.1	7tm_4	82..>212	CDD:304433	61/130 (47%)
		7tm_1	91..>277	CDD:278431	76/185 (41%)
ADRA1B	XP_011532737.1	7tm_4	57..>181	CDD:304433	58/124 (47%)
		7tm_1	62..384	CDD:278431	123/502 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010