Protein Alignment TyrRII and LOC1278365

DIOPT Version :10

• Sequence 1: NP_650651.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_061513053.1
• Gene: LOC1278365 / 1278365
• VectorBaseID: AGAMI1_001113
• Length: 701
• Species: Anopheles gambiae
• Alignment Length: 613
• Identity: 168/613 - (27%)
• Similarity: 261/613 - (42%)
• Gaps: 166/613 - (27%)

  Fly    14 SKLLSTALTVASGNS---------------------NSSDGTLLLIQTSAAPGG----------- 46
            |.|...|.|:|.|:|                     |.::..||....:||.|.
Mosquito   179 SSLAPDASTLARGSSSAGLSLSLPDLLEEDELMALWNCTNCFLLNYGAAAAAGANGTSKFYGNGT 243

  Fly    47 ----DVMATGAGAGKLGVPSMNSYLVSMAWPKSLAVAVFL-VIILVTVVGNTLVILAVLTTRRLR 106
                ||:.|  |...:.......||:     :.:|.|:.| ::||.||:||..||.|:|..|.|:
Mosquito   244 VDPRDVLPT--GEDDILASETTIYLI-----RVIATAIVLGIVILATVIGNVFVIAAILLERNLQ 301

  Fly   107 TVTNCFVMNLAITDWLVGTCVMPPSVVLYITGTWRFGWILCDIWISLDILLCSGSILSLCAISLD 171
            :|.|..:::||:.|.||...|||...|..::..||.|..|||:|.|.|:|.|:.|||.|.||:||
Mosquito   302 SVANHLILSLAVADLLVACLVMPLGAVYEVSKEWRLGADLCDMWTSSDVLCCTASILHLVAIALD 366

  Fly   172 RYLAVTQPLTYSKKRRSKRLALLMILVVWITALSITCPPYLGW----YEVGRHQAEFVDCRYNQN 232
            ||.|||. :.|:.:|.::|:. .||:::|..::.::..|.|||    :|...:|.  :.|..:|:
Mosquito   367 RYWAVTD-IDYAHQRTARRIG-YMIIIIWTLSVLVSIAPLLGWKDPEWETRVYQD--LQCIVSQD 427

  Fly   233 KGYVVFSAMGSFFIPLTVMLYVYVKIGYVLTSRRQRIVRDAYSERTADYDVDGDNFISESEHYHC 297
            .||.:|:...||::||.|:|::|.:|   ..:.|:||.|...:.:|                 |.
Mosquito   428 VGYQIFATASSFYVPLLVILFLYWRI---FLAARKRIRRRQQAAQT-----------------HP 472

  Fly   298 TP-----TKWLPNRKSRWRFNSLHDPPPSAATNAAAKGHQSSVKCSKCSKCSSATGTAG-AGAGA 356
            .|     ...|.:...||:.         .||..|:.|...:         :.|.|:.| |.|..
Mosquito   473 EPLAKASCMALTSIGFRWKV---------TATQTASGGGMIA---------NVAGGSGGIAAAVV 519

  Fly   357 GVVDKTLTFKHQPTFYELVEVSRLSSLIHCSAISCKYGGPCMHSTPSGMHYVGTEASFSDTCLGG 421
            .|:.:.|     ||..|                                    |..:|:
Mosquito   520 AVIGRPL-----PTISE------------------------------------TTTAFT------ 537

  Fly   422 NVSNNTTTTTTNTV--ALETNEKLEAE--------AKQKQQQQRSSFDHHHPHAHHHGSHGQQSH 476
            |||:..|:....::  .:| .:::|.:        |.....|...|.....|     ||.|..|
Mosquito   538 NVSSANTSPEKGSLGNGIE-RDRIEIDPPTADISMAYPSGNQASCSSTTRPP-----GSSGLAS- 595

  Fly   477 HNHHHRMPMRVST-TKRDSKTAKTLTIVMGGLIACWLPFFVYYLLIPFLPRPAVLEDLMFGFTWI 540
                 |...:.|| :||:.|.||||.|:.|..:.||||||:..:|:|......:...:.....|:
Mosquito   596 -----RKKTQSSTDSKRERKAAKTLAIITGAFVCCWLPFFIIAILLPTCTSCNISPLITSVCLWL 655

  Fly   541 GWVNCAINPFIYAFYNPDFRTAFWRLTC 568
            |:.|..:||.||..::|:||.||.|:.|
Mosquito   656 GYFNSTLNPIIYTIFSPEFRHAFKRILC 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_650651.1	7tm_GPCRs	78..>270	CDD:475119	76/196 (39%)
		TM helix 1	78..101	CDD:410628	11/23 (48%)
		TM helix 2	110..132	CDD:410628	9/21 (43%)
		TM helix 3	148..170	CDD:410628	12/21 (57%)
		TM helix 4	194..210	CDD:410628	3/15 (20%)
		TM helix 5	233..256	CDD:410628	9/22 (41%)
		7tm_GPCRs	<491..563	CDD:475119	27/71 (38%)
		TM helix 6	497..519	CDD:320098	12/21 (57%)
		TM helix 7	531..556	CDD:320098	7/24 (29%)
LOC1278365	XP_061513053.1	None