Protein Alignment TyrRII and LOC1272412

DIOPT Version :10

• Sequence 1: NP_650651.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_061498420.1
• Gene: LOC1272412 / 1272412
• VectorBaseID: AGAMI1_006350
• Length: 495
• Species: Anopheles gambiae
• Alignment Length: 568
• Identity: 164/568 - (28%)
• Similarity: 244/568 - (42%)
• Gaps: 134/568 - (23%)

  Fly    11 LPYSKLLSTALTVASGNSNSSDGTLLLIQTSAAPGGDVMATGAGAGKLGVPSMNSYLVSMAWPKS 75
            :|:..|..||||..| ..|.|.|:   ::.|...|.            .||:.::|:||:...|:
Mosquito     8 VPWEFLQLTALTNIS-FYNVSHGS---VEFSINCGS------------VVPNFSNYIVSLPNDKA 56

  Fly    76 LAVAVFLVIILVTVVGNTLVILAVLTTRRLRTVTNCFVMNLAITDWLVGTCVMPPSVVLY--ITG 138
            ..:...|:....||.||:||||||:..|.|.|.||.||.:||:.|.|||..|||.| .||  :..
Mosquito    57 GLLTFLLLFSFTTVFGNSLVILAVIRERYLHTATNYFVTSLAVADCLVGLVVMPFS-ALYEVLQN 120

  Fly   139 TWRFGWILCDIWISLDILLCSGSILSLCAISLDRYLAVTQPLTYSKKRRSKRLALLMILVVWITA 203
            ||.||...||||.|||:|..:.|||:||.||||||.|:|...:|..| .:::.|:::|..|||.:
Mosquito   121 TWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDSFSYPMK-MTRQKAVVLIAAVWICS 184

  Fly   204 LSITCPPYLGWYEVGRHQAEFVDCRYNQNKGYVVFSAMGSFFIPLTVMLYVYVKIGYVLTSRRQR 268
            .:|:.|..|.|..|.........|.:.::.||:|||::.||::||.||::.|.:|
Mosquito   185 SAISFPAILWWRAVRETDMLPFKCTFTEHLGYLVFSSIISFYLPLIVMVFTYCRI---------- 239

  Fly   269 IVRDAYSERTADYDVDGDNFISESEHYHCTPTKWLPNRKSRWRFNSLHDPPPSAATNAAAKGHQS 333
                                                     :|               ||.....
Mosquito   240 -----------------------------------------YR---------------AAAVQTR 248

  Fly   334 SVKCSKCSKCSSATGTAGAGAGAGVVDKTLTFKHQPTFYELVEVSRLSSLIHCSAISCKYGGPCM 398
            |:|          .||......:|.:..||......|..|.:...||::..|....        .
Mosquito   249 SLK----------LGTKQVLMASGELQLTLRIHRGGTTRERLNHPRLAASDHYQQF--------Q 295

  Fly   399 H---STPSGMHYVGTEASFSDTCLGGNVSNNTTTTTTNTVALETNEKLEAEAKQKQQQQRSSFDH 460
            |   ..|:....:.|:..|.       :.......|||:...:.:|           :..|:.::
Mosquito   296 HLDQMQPNTQPSLSTQHQFP-------LKKLHQLQTTNSTPDDPDE-----------EPLSALEN 342

  Fly   461 HHPHAHHHGSHGQQSHHNHHHRMPMRVSTTKRDSKTAKTLTIVMGGLIACWLPFFVYYLLIPFLP 525
            :.....|      :.|...|..:..:::...::.|.||||.||||..|.||:||||..||..|..
Mosquito   343 NGIGGRH------RVHMGKHFSLSRKLTKFAKEKKAAKTLGIVMGVFIVCWMPFFVVNLLSGFCM 401

  Fly   526 RPAVLEDLMFG-FTWIGWVNCAINPFIYAFYNPDFRTAFWRLTCRPIC 572
            .....|:::.. .||:||:|..:||.|||.::.|||.||.|:.|  :|
Mosquito   402 DCIAHEEIVSAVVTWLGWINSGMNPVIYACWSRDFRRAFLRILC--VC 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_650651.1	7tm_GPCRs	78..>270	CDD:475119	81/193 (42%)
		TM helix 1	78..101	CDD:410628	11/22 (50%)
		TM helix 2	110..132	CDD:410628	12/21 (57%)
		TM helix 3	148..170	CDD:410628	13/21 (62%)
		TM helix 4	194..210	CDD:410628	5/15 (33%)
		TM helix 5	233..256	CDD:410628	11/22 (50%)
		7tm_GPCRs	<491..563	CDD:475119	33/72 (46%)
		TM helix 6	497..519	CDD:320098	15/21 (71%)
		TM helix 7	531..556	CDD:320098	11/25 (44%)
LOC1272412	XP_061498420.1	None