Protein Alignment TyrRII and Oamb

DIOPT Version :10

• Sequence 1: NP_650651.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_061508856.1
• Gene: Oamb / 1272230
• VectorBaseID: AGAMI1_010906
• Length: 592
• Species: Anopheles gambiae
• Alignment Length: 605
• Identity: 184/605 - (30%)
• Similarity: 267/605 - (44%)
• Gaps: 143/605 - (23%)

  Fly    65 SYLVSMAW--PKSL-AVAVFLVIILVTVVGNTLVILAVLTTRRLRTVTNCFVMNLAITDWLVGTC 126
            |.|.|:.|  |.:| ::||...|.::.:|||.|||.|||.:.:||:|||.|:::||:.|.|||..
Mosquito     8 SLLASVQWTDPTNLVSLAVLAFINVLVIVGNCLVIAAVLCSHKLRSVTNFFIVSLAVADLLVGLA 72

  Fly   127 VMPPSVVLYITGTWRFGWILCDIWISLDILLCSGSILSLCAISLDRYLAVTQPLTY---SKKRRS 188
            |:|.|....:...|.||.:.|.||:::|:.:|:.|||:|||||||||:|||:|:||   ...||:
Mosquito    73 VLPFSATWEVFKVWIFGDVWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTRRA 137

  Fly   189 KRLALLMILVVWITALSITCPPYLGW----------YEVGRHQAEFV------------DCRYNQ 231
            |.|    |..:|:.:..|..||.:||          |:.|.:....|            .|....
Mosquito   138 KSL----IAGLWVLSFVICFPPLVGWKEQKVKENVYYQYGNYTLVSVTPSPAPPLPCPWTCELTN 198

  Fly   232 NKGYVVFSAMGSFFIPLTVMLYVYVKIGYVLTSRRQRIVRDAYSERTADYDVDGDNFISESEHYH 296
            :.||||:||:|||:||:.|||:.|.:| |....|..|.:...:  ||
Mosquito   199 DAGYVVYSALGSFYIPMFVMLFFYWRI-YRAAVRTTRAINQGF--RT------------------ 242

  Fly   297 CTPTKWLPNRKSRWRFN------------SLHDPPPSAATNAAAKGHQSSVKCSKCSKCSSATGT 349
               ||.:.||....|..            .||:.|.|..:..:......|....:.|:.|:....
Mosquito   243 ---TKGMGNRFDDNRLTLRIHRGRGSTSAPLHESPHSNGSTHSTTTSIGSASPERLSRYSTRGKL 304

  Fly   350 AGAGAGAGVVDKTLTFKHQPTFYELVEVSRLSSLIHCSAISCKY---GGPCMHSTPSGMHYVGTE 411
            .|.|.         |..|....:|.:::|.........|.||..   |||   |:|: :...|..
Mosquito   305 VGHGG---------TVPHPTAHHEKIKISVSYPSTENVAQSCHAEAGGGP---SSPA-VAAAGAM 356

  Fly   412 ASFSDTCLGG-------------NVSNNTTTTTTNTVALETNEK------------LEAEAKQKQ 451
            |:.|.:..||             :.:|...:..:......:.|:            |....:|:|
Mosquito   357 ATSSSSTGGGGSGGTKLLYAVHYSSANGRDSNASQIFRRPSKEQQMGSVLGGSTQYLTVSEQQQQ 421

  Fly   452 QQQRSSFDHHHPHAHHHGSHGQQSHHNH---------HHRMPMR-----VSTTKRDSKTAKTLTI 502
            |||:                 ||||...         ..||..|     |...:.::|.||||.|
Mosquito   422 QQQQ-----------------QQSHRERGSSFLSPRASKRMGKRNIKAQVKRFRMETKAAKTLAI 469

  Fly   503 VMGGLIACWLPFFVYYLLIPFLPRPAVLEDLMFGFT-WIGWVNCAINPFIYAFYNPDFRTAFWRL 566
            ::|..:.||||||..||:.||.  ...:.:|:|... |||:.|.||||.|||.::.|||.||.|:
Mosquito   470 IVGLFVLCWLPFFTMYLVRPFC--DDCINELLFSIVFWIGYCNSAINPMIYALFSKDFRFAFKRI 532

  Fly   567 TCRPICKQKRPPNHLAMFRG 586
            .||..|...|....:...||
Mosquito   533 ICRCFCSGGRFAGAVGSRRG 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_650651.1	7tm_GPCRs	78..>270	CDD:475119	87/216 (40%)
		TM helix 1	78..101	CDD:410628	11/22 (50%)
		TM helix 2	110..132	CDD:410628	10/21 (48%)
		TM helix 3	148..170	CDD:410628	11/21 (52%)
		TM helix 4	194..210	CDD:410628	3/15 (20%)
		TM helix 5	233..256	CDD:410628	14/22 (64%)
		7tm_GPCRs	<491..563	CDD:475119	33/72 (46%)
		TM helix 6	497..519	CDD:320098	12/21 (57%)
		TM helix 7	531..556	CDD:320098	13/25 (52%)
Oamb	XP_061508856.1	None