Protein Alignment TyrRII and gpr84

DIOPT Version :10

• Sequence 1: NP_650651.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001099167.2
• Gene: gpr84 / 100126017
• ZFINID: ZDB-GENE-070928-33
• Length: 402
• Species: Danio rerio
• Alignment Length: 513
• Identity: 108/513 - (21%)
• Similarity: 174/513 - (33%)
• Gaps: 161/513 - (31%)

  Fly    61 PSMNSYLVSMAWPKSLAVAVFLVIILVTVVGNTLVILAVLTTRRLRTVTNCFVMNLAITDWLVGT 125
            ||:..|       :...|.:...:.:|..:||.|.:||.:|...|||..|..::|||..|.|..|
Zfish    18 PSVEGY-------RYFGVLLGSAVTIVGTIGNILTVLAFVTDANLRTRFNVLIVNLAFADLLYCT 75

  Fly   126 CVMPPSVVLYITGTWRFGWILCDIWISLDILLCSGSILSLCAISLDRYLAVT-QPLTYSKKRRSK 189
            .:.|.||..|:...||.|...|.::..|..|..|.||::||.|::.|||.|. :..:.::...|:
Zfish    76 ILQPVSVDSYLHLHWRGGATWCRMFGLLLFLSNSVSIITLCLIAMSRYLVVAHRTSSCARLLLSQ 140

  Fly   190 RLALLMILVVWITALSITCPPYLGWYEVGRHQAEFVDCRYNQNKG--YVVFSAMGSFFIPLTVML 252
            |....:::..|:..|:...|    .:.|.....:...|.:::.||  |.            ||:|
Zfish   141 RGVAALLISSWVLGLASFAP----LWPVYVFAPQVCTCSFHRTKGRPYT------------TVLL 189

  Fly   253 YVYVKIG-------YVLTSRRQRIVRDAYSERTADYDVDGDNFISESEHYHCTPTKWLPNRKSRW 310
            ::|..:|       |.|..|:..:...|:                         .|:.|:|:|
Zfish   190 FLYFFLGLGFVGLFYFLIYRKVSVAAKAF-------------------------LKYRPSRRS-- 227

  Fly   311 RFNSLHDPPPSAATNAAAKGHQSSVKCSKCSKCSSATGTAGAGAGAGVVDKTLTFKHQPTFYELV 375
                      |....|.|:|               .|..:|..|||....
Zfish   228 ----------SKRKQAEAEG---------------TTDDSGISAGASTTQ--------------- 252

  Fly   376 EVSRLSSLIHCSAISCKYGGPCMHSTPSGMHYVGTEASFSDTCLGGNVSNNTTTTTTNTVALETN 440
                          ||:     :.|..:.....|.:|....|         ||...|...:.||.
Zfish   253 --------------SCE-----ISSDGAVAEQHGKQAQEGQT---------TTQNATQHASSETT 289

  Fly   441 EKLEAEAKQKQQQQRSSFDHHHPHAHHHGSHGQQSHHNHHHRMPMRVSTTKRDSKTAKTLTIVMG 505
            .|......|           :.|.|.:.|...:                .||.::...|:.:.
Zfish   290 SKASPVVIQ-----------NTPAAANSGEDNE----------------FKRVTRMCFTVFLC-- 325

  Fly   506 GLIACWLPFFVYYLLIPFLPRPAVLEDLMFGFTWIGWVNCAINPFIYAFYNPDFRTAF 563
             .:.|:.||.:..:.......|.|:..:....||:   |..|||.:||..|..|..|:
Zfish   326 -FVGCFAPFLLLNVADKKNRAPQVIHMICANLTWL---NSCINPLLYAAMNRQFNQAY 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_650651.1	7tm_GPCRs	78..>270	CDD:475119	56/201 (28%)
		TM helix 1	78..101	CDD:410628	7/22 (32%)
		TM helix 2	110..132	CDD:410628	8/21 (38%)
		TM helix 3	148..170	CDD:410628	8/21 (38%)
		TM helix 4	194..210	CDD:410628	2/15 (13%)
		TM helix 5	233..256	CDD:410628	6/24 (25%)
		7tm_GPCRs	<491..563	CDD:475119	18/71 (25%)
		TM helix 6	497..519	CDD:320098	4/21 (19%)
		TM helix 7	531..556	CDD:320098	8/24 (33%)
gpr84	NP_001099167.2	7tmA_GPR84-like	25..379	CDD:320338	104/497 (21%)
		TM helix 1	26..52	CDD:320338	7/25 (28%)
		TM helix 2	59..82	CDD:320338	8/22 (36%)
		TM helix 3	97..127	CDD:320338	12/29 (41%)
		TM helix 4	143..161	CDD:320338	3/21 (14%)
		TM helix 5	181..206	CDD:320338	8/36 (22%)
		TM helix 6	310..340	CDD:320338	6/48 (13%)
		TM helix 7	347..372	CDD:320338	9/27 (33%)