Protein Alignment TyrRII and taar13d

DIOPT Version :10

• Sequence 1: NP_650651.1
• Gene: TyrRII / 42135
• FlyBaseID: FBgn0038541
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001076510.1
• Gene: taar13d / 100034379
• ZFINID: ZDB-GENE-041014-62
• Length: 341
• Species: Danio rerio
• Alignment Length: 544
• Identity: 108/544 - (19%)
• Similarity: 177/544 - (32%)
• Gaps: 252/544 - (46%)

  Fly    61 PSMNSYLVSMAWPKSLAVAVFLVI---ILVTVVGNTLVILAVLTTRRLRTVTNCFVMNLAITDWL 122
            |::|:..:......|....|:|::   :.||::||::||:::...::|:|.||..||:||:.|.|
Zfish    16 PAVNNSCLKGTHHVSTQTVVYLILASAMTVTILGNSVVIISIAHFKQLQTTTNILVMSLALADLL 80

  Fly   123 VGTCVMPPSVVLYITGTWRFGWILCDIWISLDILLCSGSILSLCAISLDRYLAVTQPLTYSKKRR 187
            :|..|||.|::..:.|.|.:|...|.:..|.|:.|.|.||..|..|::||:.||..||.|.
Zfish    81 LGLVVMPFSMIRSVDGCWYYGETFCMLHSSFDLFLTSVSIFHLIFIAVDRHQAVCFPLQYP---- 141

  Fly   188 SKRLALLMILVVWITALSITCPPYLGW-----YEVG----RHQAEFVD-----------CRYNQN 232
                .::.|.|.|:..:       :.|     |..|    :...|.:|           |....|
Zfish   142 ----TMITIPVAWVMVM-------ISWSMAALYSYGLVYSKANMEGLDEYIQSMYCVGGCTLYFN 195

  Fly   233 KGYVVFSAMGSFFIPLTVMLYVYVKIGYVLTSRRQRIVRDAYSERTADYDVDGDNFISESEHYHC 297
            ..:.|...:.:||:|.:||:.:|.:| :|:..:..||:.:|...     ::||
Zfish   196 ALWSVLDTLITFFLPCSVMIGLYARI-FVVAKKHARIINEANQN-----EIDG------------ 242

  Fly   298 TPTKWLPNRKSRWRFNSLHDPPPSAATNAAAKGHQSSVKCSKCSKCSSATGTAGAGAGAGVVDKT 362
                                                                             
Zfish   243 ----------------------------------------------------------------- 242

  Fly   363 LTFKHQPTFYELVEVSRLSSLIHCSAISCKYGGPCMHSTPSGMHYVGTEASFSDTCLGGNVSNNT 427
             |||
Zfish   243 -TFK------------------------------------------------------------- 245

  Fly   428 TTTTTNTVALETNEKLEAEAKQKQQQQRSSFDHHHPHAHHHGSHGQQSHHNHHHRMPMRVSTTKR 492
                                                                        |:.:.
Zfish   246 ------------------------------------------------------------SSRRS 250

  Fly   493 DSKTAKTLTIVMGGLIACWLPFFVYYLLIPFL--PRPAVLEDLMFGFTWIGWVNCAINPFIYAFY 555
            :.|.||||.||:|..|.||||||:..|:.|::  ..|..|.:   .|.|:|::|..:||.||.|:
Zfish   251 EQKAAKTLGIVVGAFIMCWLPFFINSLMDPYINFSTPVALFE---AFVWLGYINSTMNPIIYGFF 312

  Fly   556 NPDFRTAFWRLTCRPICKQKRPPN 579
            .|.||...:.:..|.|.:    ||
Zfish   313 YPWFRKTLYLIITRRIFE----PN 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRII	NP_650651.1	7tm_GPCRs	78..>270	CDD:475119	62/214 (29%)
		TM helix 1	78..101	CDD:410628	8/25 (32%)
		TM helix 2	110..132	CDD:410628	11/21 (52%)
		TM helix 3	148..170	CDD:410628	8/21 (38%)
		TM helix 4	194..210	CDD:410628	3/15 (20%)
		TM helix 5	233..256	CDD:410628	6/22 (27%)
		7tm_GPCRs	<491..563	CDD:475119	31/73 (42%)
		TM helix 6	497..519	CDD:320098	14/21 (67%)
		TM helix 7	531..556	CDD:320098	9/24 (38%)
taar13d	NP_001076510.1	7tmA_TAARs	33..320	CDD:320183	101/509 (20%)
		TM helix 1	34..60	CDD:320183	8/25 (32%)
		TM helix 2	67..93	CDD:320183	13/25 (52%)
		TM helix 3	105..135	CDD:320183	12/29 (41%)
		TM helix 4	147..170	CDD:320183	5/29 (17%)
		TM helix 5	195..224	CDD:320183	9/29 (31%)
		TM helix 6	249..279	CDD:320183	16/29 (55%)
		TM helix 7	288..313	CDD:320183	10/27 (37%)