| Sequence 1: | NP_524393.2 | Gene: | Lgr1 / 42133 | FlyBaseID: | FBgn0016650 | Length: | 831 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_060960.2 | Gene: | LGR4 / 55366 | HGNCID: | 13299 | Length: | 951 | Species: | Homo sapiens |
| Alignment Length: | 793 | Identity: | 204/793 - (25%) |
|---|---|---|---|
| Similarity: | 340/793 - (42%) | Gaps: | 145/793 - (18%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 17 PRKGLKCLSFEFQCRLLLHHLLLTSLSGRHFVYATSAVGGALSANNCHDIH-HGFDVYPNLTAVS 80
Fly 81 LAQSTDTPLTATMPRSAWKCCCWNAS---------NQAEEVECRCEGDGLNRVPQTLTLPIQRL- 135
Fly 136 --TIASAGLPRLRHTGLKVYGSTLLDVAFTDCLQLELIQDGAFANLTLLRTIYITNAPKLTFLSK 198
Fly 199 DVFLGISDTVDIIRIINSGLTRVPDLG---HLP------------PHNI------LQMIDLDNNQ 242
Fly 243 ITRIDSKSIKVKTAQLILTNNEISYVDDSAFFG-SKIAKLSLKENKKLQMMHPNAFDGIIDITEL 306
Fly 307 DLSSTSLVGLPSAGLQNIEALYIQNTHTLKTIPSIYNFRNLQRAYLTHSFHCCAFQFPSRHDPQR 371
Fly 372 HAQRMLEIEKWRKQCKSDSGTRKERSTLDNPFNMPEDFGSFGGTDDSATDITPITFASFDYMADD 436
Fly 437 TMNKGTFHEKIILNPGDDSSAELCGNFTFRKPNIECYPMPNDLNPCEDVMGYQWLRISVWIVVAL 501
Fly 502 AVVGN-VAVLTVILSIRPESTPVPRFLMCHLAFADLCLGLYLLLVACIDAHSMGEYFNFAYDWQY 565
Fly 566 GLGCKVAGFLTVFASHLSVFTLTVITIERWLAITQAM---YLNHRIKLRPAALIMLGGWIYSMLM 627
Fly 628 SSLPLFGISNYSSTSICLPMENRDVYDTIYLIAILGSNGVAFSIIAVCYAQIYLSLGRETRQAHQ 692
Fly 693 NSPGELSVAKKMALLVFTNFACWSPIAFFG----LTALAGYPLINVTKSKILLVFFYPLNSCADP 753
Fly 754 YLYAILTSQYRQD 766 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lgr1 | NP_524393.2 | leucine-rich repeat | 182..207 | CDD:275380 | 9/24 (38%) |
| leucine-rich repeat | 208..231 | CDD:275380 | 6/37 (16%) | ||
| leucine-rich repeat | 233..256 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 257..277 | CDD:275380 | 5/20 (25%) | ||
| LRR_8 | 258..313 | CDD:290566 | 16/55 (29%) | ||
| leucine-rich repeat | 278..302 | CDD:275380 | 6/23 (26%) | ||
| leucine-rich repeat | 303..323 | CDD:275380 | 9/19 (47%) | ||
| leucine-rich repeat | 324..346 | CDD:275380 | 4/21 (19%) | ||
| 7tm_1 | 505..756 | CDD:278431 | 81/258 (31%) | ||
| LGR4 | NP_060960.2 | LRRNT | 29..56 | CDD:279764 | |
| LRR_RI | <44..239 | CDD:238064 | 30/129 (23%) | ||
| LRR 1 | 58..79 | ||||
| leucine-rich repeat | 59..82 | CDD:275380 | |||
| LRR 2 | 82..103 | ||||
| LRR_8 | 83..141 | CDD:290566 | 6/21 (29%) | ||
| leucine-rich repeat | 83..106 | CDD:275380 | |||
| LRR 3 | 106..127 | 1/5 (20%) | |||
| leucine-rich repeat | 107..130 | CDD:275380 | 2/8 (25%) | ||
| LRR 4 | 130..151 | 6/22 (27%) | |||
| LRR_8 | 131..189 | CDD:290566 | 14/63 (22%) | ||
| leucine-rich repeat | 131..154 | CDD:275380 | 6/24 (25%) | ||
| LRR 5 | 154..177 | 3/22 (14%) | |||
| leucine-rich repeat | 155..178 | CDD:275380 | 3/22 (14%) | ||
| LRR_8 | 177..237 | CDD:290566 | 17/69 (25%) | ||
| LRR 6 | 178..199 | 6/28 (21%) | |||
| leucine-rich repeat | 179..202 | CDD:275380 | 7/30 (23%) | ||
| LRR 7 | 202..223 | 2/21 (10%) | |||
| leucine-rich repeat | 203..226 | CDD:275380 | 5/23 (22%) | ||
| LRR_RI | 221..426 | CDD:238064 | 59/220 (27%) | ||
| LRR 8 | 226..247 | 5/21 (24%) | |||
| leucine-rich repeat | 227..249 | CDD:275380 | 6/22 (27%) | ||
| LRR_8 | 248..305 | CDD:290566 | 21/70 (30%) | ||
| LRR 9 | 249..270 | 9/33 (27%) | |||
| leucine-rich repeat | 250..273 | CDD:275380 | 9/35 (26%) | ||
| LRR 10 | 273..294 | 9/21 (43%) | |||
| leucine-rich repeat | 274..295 | CDD:275380 | 8/21 (38%) | ||
| LRR 11 | 320..341 | 4/20 (20%) | |||
| LRR 12 | 344..365 | 6/20 (30%) | |||
| LRR_8 | 345..401 | CDD:290566 | 14/56 (25%) | ||
| leucine-rich repeat | 345..366 | CDD:275380 | 6/20 (30%) | ||
| LRR 13 | 366..387 | 4/20 (20%) | |||
| leucine-rich repeat | 367..390 | CDD:275380 | 5/22 (23%) | ||
| LRR_8 | 390..444 | CDD:290566 | 16/54 (30%) | ||
| LRR 14 | 390..411 | 6/21 (29%) | |||
| leucine-rich repeat | 391..414 | CDD:275380 | 6/23 (26%) | ||
| LRR 15 | 414..435 | 9/20 (45%) | |||
| leucine-rich repeat | 415..438 | CDD:275380 | 9/22 (41%) | ||
| leucine-rich repeat | 439..461 | CDD:275380 | 6/21 (29%) | ||
| 7tm_1 | 556..801 | CDD:278431 | 81/257 (32%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2087 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24372 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.910 | |||||