DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pxt and ALPHA DOX2

DIOPT Version :9

Sequence 1:	NP_650648.3	Gene:	Pxt / 42131	FlyBaseID:	FBgn0261987	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_001185393.1	Gene:	ALPHA DOX2 / 843703	AraportID:	AT1G73680	Length:	640	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	136/563 - (24%)
Similarity:	226/563 - (40%)	Gaps:	136/563 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 YRSMDGTCNNPEPQRSLWGAAGQPMERMLPPAYED-GIWTPRAHSSD--------GTPLLGARKI 292
            ||:.||.||:|..  :..|:.|..:.|.:||:... |.:.......:        .|.|| |||
plant    84 YRTADGKCNHPSD--NTIGSQGSFIGRNMPPSTSQYGFFCQYFFFPENLEKKIVVATKLL-ARK- 144

  Fly   293 SRTLLSDVDRPHPKYNLMVMQFGQVLAHDISQTSSIRLEDGSLVQCCSPEGKVALSPQQSHFACM 357
              ..:.:.|    ::|::...:.|.:.||...    .|||                   :|
plant   145 --RFIDNGD----QFNVIACSWIQFMIHDWVD----HLED-------------------TH---- 176

  Fly   358 PIHVEPDDEFFSAFGVRCLNFVRLSLVPSPDCQLSYGKQLTKVTHFVDASPVYGSSDEASRSLRA 422
            .|.:|..:|..|...::...|:|...||:.|...| |...|: |.:.|.|.:||:.:...|.:|.
plant   177 QIELEAPEEVASGCPLKSFKFLRTKKVPTDDHHKS-GAVNTR-TPWWDGSVIYGNDETGMRRVRV 239

  Fly   423 FRGGRLRMMNDFGRDLLPLTNDKKACPSEEAGKSCFHSGDGRTNQIISLITLQILLAREHNRVAG 487
            |:.|:|::..| |.    |..|::..|.         |||.| |.......||.|..:|||.|..
plant   240 FKDGKLKISGD-GL----LERDERGVPI---------SGDIR-NSWSGFSLLQALFVKEHNSVCD 289

  Fly   488 ALHELNPSASDETLFQEARRI---VIAEMQHITYN-EFL---PIIIG------------PQQMKR 533
            .|.|..|...||.|::.||.:   |||::..|.:. |.|   .:..|            .:.|..
plant   290 MLKERYPDFDDEKLYRTARLVTAAVIAKVHTIDWTIELLKTDTLTAGMRINWYGFFGKKVKDMVG 354

  Fly   534 FRLVPLHQGY-----SHDYNVNVNPAITNEFSGAAYRMGHSSVDGKFQIR--------QEHGRID 585
            .|..||..|.     .:|:.|..  ::|.||. :.||| |..:.....:|        :|:..|:
plant   355 ARFGPLFSGLVGLKKPNDHGVPY--SLTEEFV-SVYRM-HCLLPETLILRDMNSENVDKENPAIE 415

  Fly   586 EVVNIPDVMFNPSRMRKREF-YDDML----------RTLYSQP-------MQQVDSSISQGLSRF 632
            ..:.:.:::...:..:..:. ::.:|          .||::.|       .|.:|..
plant   416 REIPMTELIGKKAGEKASKLGFEQLLVSMGHQSCGALTLWNYPNWMRNLVAQDIDGE-------- 472

  Fly   633 LFRGDNPFGLDLAAINIQRGRDQGLRSYNDYLELMGAPKLHSFEQF--PIEIAQKLSRVYRTPDD 695
                |.|..:|:||:.|.|.|::|:..||::.:.:....:..:|:.  ..|..:.|..||.  ||
plant   473 ----DRPHLIDMAALEIYRDRERGVPRYNEFRKNLLMSPISKWEELTDDEEAIKVLREVYE--DD 531

  Fly   696 I---DLWVGGLLEKAVEGGVVGVTFAEIIADQFARFKQGDRYY 735
            |   ||.||...||.::|..:..|...|.....:|..:.||::
plant   532 IEKLDLNVGLHAEKKIKGFAISETAFFIFLLVASRRLEADRFF 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pxt	NP_650648.3	GH64-TLP-SF	<67..119	CDD:295337
		An_peroxidase	237..772	CDD:281139	136/563 (24%)
		peroxinectin_like	396..767	CDD:188655	97/395 (25%)
ALPHA DOX2	NP_001185393.1	PLN02283	1..640	CDD:177921	136/563 (24%)
ALPHA DOX2	NP_001185393.1	An_peroxidase	84..609	CDD:281139	136/563 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2076
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870