DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pxt and DOX1

DIOPT Version :9

Sequence 1:	NP_650648.3	Gene:	Pxt / 42131	FlyBaseID:	FBgn0261987	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_186791.1	Gene:	DOX1 / 821135	AraportID:	AT3G01420	Length:	639	Species:	Arabidopsis thaliana

Alignment Length:	553	Identity:	127/553 - (22%)
Similarity:	216/553 - (39%)	Gaps:	123/553 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 YRSMDGTCNNP-----EPQRSLWGAAGQPMERMLPPAYEDGIWTPRAHSSD----GTPLLGARKI 292
            ||:.||..|:|     ..|.|.:|       |..||..:..    :....|    .|.|||.:|.
plant    90 YRTADGKFNDPFNEGVGSQNSFFG-------RNCPPVDQKS----KLRRPDPMVVATKLLGRKKF 143

  Fly   293 SRTLLSDVDRPHPKYNLMVMQFGQVLAHDISQTSSIRLEDGSLVQCCSPEGKVALSPQQSHFACM 357
            ..|        ..::|::...:.|.:.||...    .|||...::..:|:...:..|..|
plant   144 IDT--------GKQFNMIAASWIQFMIHDWID----HLEDTHQIELVAPKEVASKCPLSS----- 191

  Fly   358 PIHVEPDDEFFSAFGVRCLNFVRLSLVPSPDCQLSYGKQLTKVTHFVDASPVYGSSDEASRSLRA 422
                              ..|::...||:...::..|.|..: |.:.|:|.:|||:.:....:|.
plant   192 ------------------FRFLKTKEVPTGFFEIKTGSQNIR-TPWWDSSVIYGSNSKTLDRVRT 237

  Fly   423 FRGGRLRMMNDFGRDLLPLTNDKKACPSEEAGKSCFHSGDGRTNQIISLITLQILLAREHNRVAG 487
            ::.|:|::..:.|..|           .:|.|.:.  |||.| |....:..||.|..:|||.|..
plant   238 YKDGKLKISEETGLLL-----------HDEDGLAI--SGDIR-NSWAGVSALQALFIKEHNAVCD 288

  Fly   488 ALHELNPSASDETLFQEARRI---VIAEMQHITYNEFL----PIIIGPQQM------KRFRLVPL 539
            ||.:.:....||.|::.||.:   |:|::..|.:...|    .::.|.:..      |:|:....
plant   289 ALKDEDDDLEDEDLYRYARLVTSAVVAKIHTIDWTVQLLKTDTLLAGMRANWYGLLGKKFKDSFG 353

  Fly   540 HQGYS---------HDYNVNVNPAITNEFSGAAYRMGHSSVDGKFQIRQEHGRIDEVVN------ 589
            |.|.|         ...|..|..::|.:|: :.||| ||.:..:..|..    ||:|..
plant   354 HAGSSILGGVVGMKKPQNHGVPYSLTEDFT-SVYRM-HSLLPDQLHILD----IDDVPGTNKSLP 412

  Fly   590 -IPDVMFNPSRMRKREFYDDMLRTLYSQPMQQVDSSISQGLS--------RFLFRGD-----NPF 640
             |.::.......||.|  :.|....:::.|..:....|..|.        |.:...|     .|.
plant   413 LIQEISMRDLIGRKGE--ETMSHIGFTKLMVSMGHQASGALELMNYPMWLRDIVPHDPNGQARPD 475

  Fly   641 GLDLAAINIQRGRDQGLRSYNDYLELMGAPKLHSFEQF--PIEIAQKLSRVY-RTPDDIDLWVGG 702
            .:||||:.|.|.|::.:..||::...|....:..:|..  ..|..:.|..|| ...:::||.||.
plant   476 HVDLAALEIYRDRERSVPRYNEFRRSMFMIPITKWEDLTEDEEAIEVLDDVYDGDVEELDLLVGL 540

  Fly   703 LLEKAVEGGVVGVTFAEIIADQFARFKQGDRYY 735
            :.||.::|..:..|...|......|..:.||::
plant   541 MAEKKIKGFAISETAFYIFLIMATRRLEADRFF 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pxt	NP_650648.3	GH64-TLP-SF	<67..119	CDD:295337
		An_peroxidase	237..772	CDD:281139	127/553 (23%)
		peroxinectin_like	396..767	CDD:188655	94/385 (24%)
DOX1	NP_186791.1	PLN02283	6..639	CDD:177921	127/553 (23%)
DOX1	NP_186791.1	An_peroxidase	90..608	CDD:281139	127/553 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2076
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870