Protein Alignment Pxt and Duox

DIOPT Version :10

• Sequence 1: NP_650648.3
• Gene: Pxt / 42131
• FlyBaseID: FBgn0261987
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_608715.2
• Gene: Duox / 33477
• FlyBaseID: FBgn0283531
• Length: 1537
• Species: Drosophila melanogaster
• Alignment Length: 573
• Identity: 163/573 - (28%)
• Similarity: 263/573 - (45%)
• Gaps: 109/573 - (19%)

  Fly   241 DGTCNN---PEPQRSLWGAAGQPMERMLPPAYEDGIWTPRAHSSDGTPLLGARKISRTLLSDVDR 302
            ||..||   |:     ||:....:.|..||:|.||::.....:...|     |::||..:...|.
  Fly    73 DGWYNNLAHPD-----WGSVDSHLVRKAPPSYSDGVYAMAGANRPST-----RRLSRLFMRGKDG 127

  Fly   303 PHPKYN--LMVMQFGQVLAHDISQTSSIRLEDGSLVQCCSPEGKVALSPQQSHFACMPIHVEPDD 365
            ...|:|  .::..|||::|::|...|    |.|     |         |.:.|    .|.:|..|
  Fly   128 LGSKFNRTALLAFFGQLVANEIVMAS----ESG-----C---------PIEMH----RIEIEKCD 170

  Fly   366 EFF--SAFGVRCLNFVRLS----LVPSPDCQLSYGKQLTKVTHFVDASPVYGSSDEASRSLRAFR 424
            |.:  ...|.:.:.|.|.:    ...||:..   .:|:.::|.::|.|.:|.:|:....::|:|.
  Fly   171 EMYDRECRGDKYIPFHRAAYDRDTGQSPNAP---REQINQMTAWIDGSFIYSTSEAWLNAMRSFH 232

  Fly   425 GGRLRMMNDFGRDLLPLTNDKKA------CPSEE---AGKSCFHSGDGRTNQIISLITLQILLAR 480
            .|.|....| |:  ||:.|..:.      .||..   :.:..|..||.||||..::::..||..|
  Fly   233 NGTLLTEKD-GK--LPVRNTMRVPLFNNPVPSVMKMLSPERLFLLGDPRTNQNPAILSFAILFLR 294

  Fly   481 EHNRVAGALHELNPSASDETLFQEARRIVIAEMQHITYNEFLPIIIGPQQMKRFRLVPLHQGYSH 545
            .||.:|..:..::|..|||.::|.||..|||.:|::...|:||..:|..       :|.::||..
  Fly   295 WHNTLAQRIKRVHPDWSDEDIYQRARHTVIASLQNVIVYEYLPAFLGTS-------LPPYEGYKQ 352

  Fly   546 DYNVNVNPAITNEFSGAAYRMGHSSV-------DGKFQIRQEHGRIDEVVNIPDVMFNPSRMRKR 603
            |    ::|.|.:.|..||:|.||:.:       ||:...:      :..:..|.|....:.....
  Fly   353 D----IHPGIGHIFQAAAFRFGHTMIPPGIYRRDGQCNFK------ETPMGYPAVRLCSTWWDSS 407

  Fly   604 EFY-----DDMLRTLYSQPMQQVDSSISQGLSRFLFRGDNPF-GLDLAAINIQRGRDQGLRSYND 662
            .|:     :::|..|.||..::.|..:...:...|| |...| ..||.|:||.||||.||..||.
  Fly   408 GFFADTSVEEVLMGLASQISEREDPVLCSDVRDKLF-GPMEFTRRDLGALNIMRGRDNGLPDYNT 471

  Fly   663 YLELMGAPKLHS---------FEQFPIEIAQKLSRVYRTP-DDIDLWVGGLLEKAVEGGVVGVTF 717
            ..|..|. |.|.         ||..| |:...|...|... ||:|::|||:||..   |..|..|
  Fly   472 ARESYGL-KRHKTWTDINPPLFETQP-ELLDMLKEAYDNKLDDVDVYVGGMLESY---GQPGEFF 531

  Fly   718 AEIIADQFARFKQGDRYYYEYD-NGINPGAFNPLQLQEIRKVTLARLLCDNSD 769
            ..:|.:||.|.:..||:::|.: |||    |.|.::.|:||:||..::.:::|
  Fly   532 TAVIKEQFQRLRDADRFWFENERNGI----FTPEEIAELRKITLWDIIVNSTD 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxt	NP_650648.3	An_peroxidase	237..781	CDD:460804	163/573 (28%)
Duox	NP_608715.2	dual_peroxidase_like	72..625	CDD:188652	163/573 (28%)
		PTZ00184	807..965	CDD:185504
		EFh	860..921	CDD:238008
		PLN02844	<1081..>1393	CDD:215453
		NOX_Duox_like_FAD_NADP	1265..1536	CDD:99783