DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pxt and Igsf9b

DIOPT Version :9

Sequence 1:	NP_650648.3	Gene:	Pxt / 42131	FlyBaseID:	FBgn0261987	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	56/250 - (22%)
Similarity:	85/250 - (34%)	Gaps:	51/250 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PAPLATSTESSKKPEKATSGLLKKCLPCSDGIRCVPQIQCPAHVRMESHEKPQICDLPAGKFGYC 104
            |||.||..:........:.|.|:.   .|.|:. :|.:..|.......|..|       ..||
  Rat  1118 PAPPATKWQERPMQPLVSQGQLRH---TSQGMG-IPVLPYPEPAEPGGHGGP-------STFG-- 1169

  Fly   105 CETGQNHTAPKPETSPKERRSGFPTILSPAVLDEARRNFEHLMHGVAQIPV--RRGFPDFA---- 163
            .:|......|:|..||::.|...|: |...||..:|      :..:.|.|:  |.|.|:.|
  Rat  1170 LDTRWYEPQPRPRPSPRQARRAEPS-LHQVVLQPSR------LSPLTQSPLSSRTGSPELAARAR 1227

  Fly   164 --HGLVFHSTAKDDLHNFAISNSA---IEQVMTTQLFGKKEQVPVEDFITNNVPIKFTETPLAHH 223
              .||:    .:.::....:...|   ..:..|....|...|.......:....:.||.....:.
  Rat  1228 PRPGLL----QQAEMSEITLQPPAAVSFSRKSTPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYP 1288

  Fly   224 CQP----PPVCGNIRSVY------RSMDGTCNNPEPQRSLWGAAGQPMERMLPPA 268
            ..|    ||..|:...|:      |.|......|||..:|      |...:||||
  Rat  1289 SPPPGPAPPAPGDNLDVFGQTPSPRRMGEEPLRPEPPTTL------PTSGILPPA 1337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pxt	NP_650648.3	GH64-TLP-SF	<67..119	CDD:295337	11/51 (22%)
		An_peroxidase	237..772	CDD:281139	10/37 (27%)
		peroxinectin_like	396..767	CDD:188655
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021	34/151 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332		52/243 (21%)
		Ig	41..115	CDD:319273
		I-set	139..225	CDD:369462
		Ig	229..321	CDD:386229
		Ig	<353..414	CDD:386229
		Ig	438..502	CDD:319273
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900