Protein Alignment Pxt and Ptgs2

DIOPT Version :9

• Sequence 1: NP_650648.3
• Gene: Pxt / 42131
• FlyBaseID: FBgn0261987
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_058928.3
• Gene: Ptgs2 / 29527
• RGDID: 620349
• Length: 604
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 126/610 - (20%)
• Similarity: 212/610 - (34%)
• Gaps: 165/610 - (27%)

  Fly   207 ITNNVP------IKFTETPLAHHCQPPPVCGNIRSVYRSMDGTCNNPEPQRSLWGAAGQPMERML 265
            |.||:|      :::..|..:|....||.. |:...|:|.:...|     .|.:       .|.|
  Rat    87 IVNNIPFLRNSIMRYVLTSRSHLIDSPPTY-NVHYGYKSWEAFSN-----LSYY-------TRAL 138

  Fly   266 PPAYEDGIWTPRAHSSDGTPLLGARK--ISRTLLSDVDRPHPK-YNLMVMQFGQVLAHDISQTSS 327
            ||..:|   .|......|...|...|  :.:.||.....|.|: .|:|...|.|...|
  Rat   139 PPVADD---CPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGTNMMFAFFAQHFTH------- 193

  Fly   328 IRLEDGSLVQCCSPEGKVALSPQQSHFACMPIHVEPDDEFFSAFGVRCLNFVRLSLVPSPDCQLS 392
                                                  :||.....|...|.|
  Rat   194 --------------------------------------QFFKTDQKRGPGFTR------------ 208

  Fly   393 YGKQLTKVTHFVDASPVYGSSDEASRSLRAFRGGRLRMMNDFGRDLLPLTNDKKA---CPSEEAG 454
                  .:.|.||.:.|||.:.:....||.|:.|:|:.....|....|...|.:.   .|.....
  Rat   209 ------GLGHGVDLNHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKDTQVDMIYPPHVPE 267

  Fly   455 KSCFHSGDGRTNQIISLITLQILLAREHNRVAGALHELNPSASDETLFQEARRIVIAE------- 512
            ...|..|......:..|:....:..||||||...|.:.:|...||.|||.:|.|:|.|
  Rat   268 HLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTSRLILIGETIKIVIE 332

  Fly   513 --MQHIT-YN---EFLPIIIGPQQMKRFRLVPLHQGYSHDYNVNVNPAITNEFSGAAYRMGHSSV 571
              :||:: |:   :|.|.::..||.:          |.:        .|.:||:
  Rat   333 DYVQHLSGYHFKLKFDPELLFNQQFQ----------YQN--------RIASEFN----------- 368

  Fly   572 DGKFQIRQEHGRIDEVVNIPDVMFNPSRMRKREFYDDMLRTLYSQPMQQVDSSISQGLSRFLFRG 636
                .:...|..:.:..||.|..:.    .|:..|::.:  |....:.....|.::.::..:..|
  Rat   369 ----TLYHWHPLLPDTFNIEDQEYT----FKQFLYNNSI--LLEHGLAHFVESFTRQIAGRVAGG 423

  Fly   637 DN-PFGLD-LAAINIQRGRDQGLRSYNDYLELMGAPKLHSFEQF--PIEIAQKLSRVYRTPDDID 697
            .| |..:. :|..:|.:.|:...:|.|:|.:........|||:.  ..|:|.:|..:|...|.::
  Rat   424 RNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYHDIDAME 488

  Fly   698 LWVGGLLEKAVEGGVVGVTFAEIIADQFARFKQGD-----RYYYEYDNGINPGAF-NPLQLQEIR 756
            |:...|:||.....:.|.|..|:.|....:...|:     :|:       .|..| ..:..:.|.
  Rat   489 LYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYW-------KPSTFGGEVGFRIIN 546

  Fly   757 KVTLARLLCDNSDRLTLQAVPLAAF 781
            ..::..|:|:|     ::..|.|:|
  Rat   547 TASIQSLICNN-----VKGCPFASF 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxt	NP_650648.3	GH64-TLP-SF	<67..119	CDD:295337
		An_peroxidase	237..772	CDD:281139	114/563 (20%)
		peroxinectin_like	396..767	CDD:188655	86/396 (22%)
Ptgs2	NP_058928.3	EGF	21..53	CDD:278437
		prostaglandin_endoperoxide_synthase	75..562	CDD:188648	123/604 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810