Protein Alignment Pxt and ptgs2a

DIOPT Version :10

• Sequence 1: NP_650648.3
• Gene: Pxt / 42131
• FlyBaseID: FBgn0261987
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_705943.1
• Gene: ptgs2a / 246227
• ZFINID: ZDB-GENE-020530-2
• Length: 601
• Species: Danio rerio
• Alignment Length: 600
• Identity: 131/600 - (21%)
• Similarity: 209/600 - (34%)
• Gaps: 157/600 - (26%)

  Fly   223 HCQPPPVCGNIRSVYRSMDGTCNNPEPQ---------RSLWGAAGQPMERMLPPAYEDGIWTPRA 278
            :|..|.:...|:|..:        |.|.         :|:|                 .|....:
Zfish    56 NCTTPELLTRIKSALK--------PRPNVVHHILTHYKSIW-----------------DIINSIS 95

  Fly   279 HSSDGTPLLGARKISRTLLSDVDRPHPKYNLMVMQFGQVLAHDISQTSSIRLEDGSLVQCCS--- 340
            :..||  ::....:||:.|  |:.| |.||   ..:|.......|..|........|.|.|.
Zfish    96 YLRDG--IMRYILLSRSHL--VESP-PTYN---ADYGYKSWEAYSNLSYYTRTLAPLPQNCPTPD 152

  Fly   341 -PEGKVAL-----------SPQQSH--FACMPIHVEPDDEFFSAFGVRCLNFVRLSLVPSPDCQL 391
             |..|..:           .||:|.  ||....|.  ..:||.:                   ..
Zfish   153 LPNAKQVVEQVLLRKQFIPDPQRSSLMFAFFAQHF--SHQFFKS-------------------DF 196

  Fly   392 SYGKQLTK-VTHFVDASPVYGSSDEASRSLRAFRGGRLRMMNDFGRDLLPLTNDKKA-------C 448
            ..|...|| :.|.||...:||.:.|....||.|:.|:|:.....|....||..|.:.       .
Zfish   197 KKGPAFTKALGHGVDLGHIYGETLEVQHKLRLFKDGKLKYQVVDGEVYPPLVKDVQVEMHYPPHI 261

  Fly   449 PSEEAGKSCFHSGDGRTNQIISLITLQILLAREHNRVAGALHELNPSASDETLFQEARRIVIAE- 512
            |.|:.    |..|......:..|:....:..||||||...:.:.:|...||.:||..|.|:|.|
Zfish   262 PEEQK----FAVGHEAFGLVPGLMMYATIWLREHNRVCDIMKQEHPDWDDERIFQTTRLILIGET 322

  Fly   513 --------MQHIT-YN---EFLPIIIGPQQMKRFRLVPLHQGYSHDYNVNVNPAITNEFSGAAYR 565
                    :||:: ||   :|.|.:|..:   ||:       |.:        .|..||: ..|.
Zfish   323 IKIVIEDYVQHLSGYNFKLKFDPELIFSE---RFQ-------YQN--------RIAAEFN-TLYH 368

  Fly   566 MGHSSVDGKFQIRQEHGRIDEVVNIPDVMFNPSRMRKREFYDDMLRTLYSQPMQQVDSSISQGLS 630
            . |..:...|||:      |::......:||.|.:....     :|.:.....:|....:|.|
Zfish   369 W-HPLLPDNFQIQ------DQIYGYHQFVFNNSIVTTHG-----IRNMVDSFTKQTAGRVSGG-- 419

  Fly   631 RFLFRGDNPFGLDLAAINIQRGRDQGLRSYNDYLELMGAPKLHSFEQF--PIEIAQKLSRVYRTP 693
                |...|....:|...:::.|....:|:|.|..........|||:.  ..::|.:|..:|...
Zfish   420 ----RNLPPAVQGVAVKVLEQTRQMRYQSFNAYRRRFNMKPYSSFEEMTGDKDLAAQLKELYGHV 480

  Fly   694 DDIDLWVGGLLEKAVEGGVVGVTFAEIIADQFARFKQGD-----RYYYEYDNGINPGAF-NPLQL 752
            |.::|:.|.|:||:....|.|.|..|:.|....:...|:     .|:       .|..| ..:..
Zfish   481 DKVELYPGLLVEKSRPNSVFGETMVEMGAPYSLKGLMGNAICSPEYW-------KPSTFGGKVGF 538

  Fly   753 QEIRKVTLARLLCDN 767
            ..:...:|.:|:|.|
Zfish   539 DIVNSASLKKLVCLN 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxt	NP_650648.3	An_peroxidase	237..781	CDD:460804	126/585 (22%)
ptgs2a	NP_705943.1	EGF_CA	25..58	CDD:238011	0/1 (0%)
		prostaglandin_endoperoxide_synthase	78..559	CDD:188648	124/569 (22%)