Protein Alignment Pxt and ptgs1

DIOPT Version :9

• Sequence 1: NP_650648.3
• Gene: Pxt / 42131
• FlyBaseID: FBgn0261987
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_705942.1
• Gene: ptgs1 / 246226
• ZFINID: ZDB-GENE-020530-1
• Length: 597
• Species: Danio rerio
• Alignment Length: 631
• Identity: 135/631 - (21%)
• Similarity: 217/631 - (34%)
• Gaps: 168/631 - (26%)

  Fly   216 TETPLAHH-CQPPPVCGNIRSVYRSMDGT--------CNNPEPQRSLWGAAGQPMERMLPPA--- 268
            |..|..:: ||...:|..........|.|        |..||    ||    ..:.|:|.|:
Zfish    32 TANPCCYYPCQNQGICVRYGLERYECDCTRTGYYGENCTIPE----LW----TRVYRLLKPSPNV 88

  Fly   269 ------YEDGIWTPRAHSSDGTPLLGARKISRTLLSD-------------VDRPHPKYNLM---- 310
                  :.|.:|.               .|:|:.|.|             :..| |.||..
Zfish    89 VHYILTHFDWLWD---------------LINRSFLRDWLMRKVLTVRANLIPSP-PTYNSRYDYL 137

  Fly   311 -------VMQFGQVL---AHD----ISQTSSIRLEDGS-LVQCCSPEGKVALSPQQSH--FACMP 358
                   :..:.::|   .:|    :.....|:|.|.. ||:.........|.||.::  ||...
Zfish   138 NWEAYSNITYYTRILPPVPNDCPTPMGTKGKIKLPDPKLLVEKFMLRRNFRLDPQGTNLMFAFFA 202

  Fly   359 IHVEPDDEFFSAFGVRCLNFVRLSLVPSPDCQLSYGKQLTKVTHFVDASPVYGSSDEASRSLRAF 423
            .|.  ..:||.......|.|.:                  .:.|.|||..:||.|.:....||..
Zfish   203 QHF--THQFFKTHNRVGLGFTK------------------GLGHGVDAGHIYGDSLDRQLELRLH 247

  Fly   424 RGGRLR--MMNDFGRDLLPLT----NDKKACPSEEAGKSCFHSGDGRTNQIISLITLQILLAREH 482
            :.|:|:  ::|.   |:.|.|    ..|.:.|.....:.....|......:..|.....|..|||
Zfish   248 KDGKLKYQVLNG---DIYPPTVLHAQVKMSYPPSVPPEQQLAIGQEVFGLLPGLGMYATLWLREH 309

  Fly   483 NRVAGALHELNPSASDETLFQEARRIVIAEMQHITYNEFLPIIIGPQQMKRFRLVPLH------- 540
            |||...|.:.:|:..||.|||.||.|:|.|...|...|::      |.:..:|| .||
Zfish   310 NRVCEILKQEHPTWGDEQLFQTARLIIIGETIRIVIEEYV------QHLSGYRL-KLHFDPTLLF 367

  Fly   541 -QGYSHDYNVNVNPAITNEFSGAAYRMGHSSVDGKFQIRQEHGRIDEVVNIPDVMFNPSRMRKRE 604
             ..:.:...::|      ||:...:  .|..:...|.|..:|      :.....:||.|.:....
Zfish   368 NSQFQYQNRISV------EFNQLYH--WHPLMPDSFYIDGDH------IQYSKFIFNTSILTHYG 418

  Fly   605 FYDDMLRTLYSQPMQQVDSSISQGLSRFLFRGDN--PFGLDLAAINIQRGRDQGLRSYNDYLELM 667
            . :.::.....||..|:..            |.|  |....:|...|...|:..|:.:|:|.:..
Zfish   419 L-EKLVEAFSIQPAGQIGG------------GHNIHPVVSGVAERVIVESRELRLQPFNEYRKRF 470

  Fly   668 GAPKLHSF-----EQFPIEIAQKLSRVYRTPDDIDLWVGGLLEKAVEGGVVGVTFAEIIADQFAR 727
            ......||     ||   |::::|..:|...|.::.:...||||...|.|.|.:..|:.|....:
Zfish   471 NLKPYTSFAELTGEQ---EMSKELEELYGHIDAMEFYPALLLEKTRPGAVFGESMVEMGAPFSLK 532

  Fly   728 FKQGDRY----YYEYDNGINPGAF-NPLQLQEIRKVTLARLLCDNS 768
            ...|:..    |::      |..| .......:...||.:|:|.|:
Zfish   533 GLMGNPICSPDYWK------PSTFGGKTGFDIVNSATLKKLVCLNT 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxt	NP_650648.3	GH64-TLP-SF	<67..119	CDD:295337
		An_peroxidase	237..772	CDD:281139	130/609 (21%)
		peroxinectin_like	396..767	CDD:188655	92/396 (23%)
ptgs1	NP_705942.1	EGF	36..68	CDD:278437	5/31 (16%)
		prostaglandin_endoperoxide_synthase	90..576	CDD:188648	120/565 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810