DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pxt and Igsf9b

DIOPT Version :9

Sequence 1:	NP_650648.3	Gene:	Pxt / 42131	FlyBaseID:	FBgn0261987	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	390	Identity:	80/390 - (20%)
Similarity:	124/390 - (31%)	Gaps:	100/390 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PAPLATSTESSKKPEKATSGLLKKCLPCSDGIRCVPQIQCPAHVRMESHEKPQICDLPAGKFGYC 104
            |||.||..:........:.|.|:.   .|.|:. :|.:..|.......|..|       ..||
Mouse  1120 PAPPATKWQERPMQPLVSQGQLRH---TSQGMG-IPVLPYPEPAEPGGHGGP-------STFG-- 1171

  Fly   105 CETGQNHTAPKPETSPKERRSGFPTILSPAVLDEARRNFEHLMHGVAQIPV--RRGFPDFA---- 163
            .:|......|:|..||::.|...|: |...||..:|      :..:.|.|:  |.|.|:.|
Mouse  1172 LDTRWYEPQPRPRPSPRQARRAEPS-LHQVVLQPSR------LSPLTQSPLSSRTGSPELAARAR 1229

  Fly   164 --HGLVFHSTAKDDLHNFAISNSA---IEQVMTTQLFGKKEQVPVEDFITNNVPIKFTETPLAHH 223
              .||:    .:.::....:...|   ..:..|....|...|.......:....:.||.....:.
Mouse  1230 PRPGLL----QQAEMSEITLQPPAAVSFSRKSTPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYP 1290

  Fly   224 CQP----PPVCGNIRSVY------RSMDGTCNNPEPQRSLWGAAGQPMERMLPPAYEDGIWTPRA 278
            ..|    ||..|:...|:      |.|......|||..:|      |...:||||..:.....|.
Mouse  1291 SPPPGPAPPAPGDTLDVFGQTPSPRRMGEEPLRPEPPTTL------PTSGILPPAPGNAAVPERL 1349

  Fly   279 HSSDGTPLLGARKISRTLLSDVDRPHPKYNLMVMQFGQVLAHDISQTSSIRLEDGSLVQCCSPEG 343
            .:      |..::|.:          ||.:            ....:.|.:..|||..|......
Mouse  1350 EA------LRYQRIKK----------PKKS------------SKGSSKSKKRSDGSASQAQQLPS 1386

  Fly   344 KVALSPQQSHFACM---PIHVEPDDEFFSAFGVRCLNFVRLSLVPSPDCQLSYGKQLTKVTHFVD 405
            ...|.|.::  .|:   ..|..||.            |.|||.:    |.....:..|.:.:.||
Mouse  1387 SQVLWPDEA--VCLRKKKRHSRPDP------------FARLSDL----CHRQLPEDQTAILNSVD 1433

Fly 406 405
Mouse 1434 1433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pxt	NP_650648.3	GH64-TLP-SF	<67..119	CDD:295337	11/51 (22%)
		An_peroxidase	237..772	CDD:281139	35/178 (20%)
		peroxinectin_like	396..767	CDD:188655	3/10 (30%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273
		I-set	141..227	CDD:369462
		Ig	231..323	CDD:386229
		Ig	<355..416	CDD:386229
		Ig	440..504	CDD:319273
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021	34/151 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900