Protein Alignment Pxt and duox2

DIOPT Version :10

• Sequence 1: NP_650648.3
• Gene: Pxt / 42131
• FlyBaseID: FBgn0261987
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: XP_017947900.2
• Gene: duox2 / 100486050
• XenbaseID: XB-GENE-6047411
• Length: 1517
• Species: Xenopus tropicalis
• Alignment Length: 601
• Identity: 152/601 - (25%)
• Similarity: 248/601 - (41%)
• Gaps: 99/601 - (16%)

  Fly   241 DGTCNNPEPQRSLWGAAGQPMERMLPPAYEDGIW---------TPRAHSSDGTPLLGARKISRTL 296
            ||..||.....:  |:.|..:.|.:|..|.||::         .||:.|:..|........||.|
 Frog    30 DGWYNNLAYHST--GSPGSKLLRHIPAFYTDGVYQVPKEPELPNPRSISNVVTKGKSGLPSSRNL 92

  Fly   297 LSDVDRPHPKYNLMVMQFGQVLAHDISQTS---------SIRLEDGSLVQCCSPEGKVALSPQQS 352
                       .:|.:.||..:..::..|.         :|.:..|.||...:...||.:..|:|
 Frog    93 -----------TVMAISFGYHVLSEVVYTGKPACPAEFLNIEIPKGDLVFDRTNTSKVVIPFQRS 146

  Fly   353 HFACMPIHVEPDDEFFSAFGVRCLNFVRLSLVPSPDCQLSYGKQLTKVTHFVDASPVYGSSDEAS 417
            .:       .||..       |..|..|              ..:..|:.::|.|.:||||....
 Frog   147 KW-------YPDTG-------RSPNNPR--------------DHVNSVSAWIDGSSIYGSSHSWC 183

  Fly   418 RSLRAFRGGRLRMMND-----FGRDLLPLTNDKKACPSEEAGKSCFHSGDGRTNQIISLITLQIL 477
            .:||.|.||:|....|     |.:..||:.........|......:..|:.|.|:...|.:|.||
 Frog   184 DALRNFSGGKLASGPDEGVPRFAKSDLPMWKVPNPSTGETGNNGLYAFGNARANESPFLQSLGIL 248

  Fly   478 LAREHNRVAGALHELNPSASDETLFQEARRIVIAEMQHITYNEFLPIIIGPQQMKRFRLVPLHQG 542
            ..|.||..|....:.||..|||.|||.||:.|||..|:|.:.|:||..:.       |.|..::|
 Frog   249 WFRYHNYKAQEFAKENPEWSDEVLFQHARKWVIAVYQNIVFYEWLPAFLS-------RNVTAYKG 306

  Fly   543 YSHDYNVNVNPAITNEFSGAAYRMGHSSV-----DGKFQ-IRQEHGRIDEVVNIPDVMFN--PSR 599
            |....:.:::|..|.:.|...|.|..|.:     |..|| :...:|.:...:.:.:..:|  .|.
 Frog   307 YQQHVDPSISPVFTVQLSQMIYTMMPSGIYMRNKDCNFQNVSGSNGSVWPALRLCNNYWNRENSN 371

  Fly   600 MRKREFYDDMLRTLYSQPMQQVDSSISQGLSRFLFRGDNPFGLDLAAINIQRGRDQGLRSYNDYL 664
            ::.....|::|..:.||..::.|:.:...|:.:.:........||.|.:|...||.||.:||...
 Frog   372 LKNSSSTDEILMGMASQIAEKEDNILVNDLTDYCYGQIKYSRTDLFAASILHARDLGLPNYNKVC 436

  Fly   665 ELMGAPKLHSFEQF-PIEIAQKLSRVYRTPDDIDLWVGGLLEKAVEGGVVGVTFAEIIADQFARF 728
            |....|.|.::|:. ..|:.:||:.:|....:...::.|||.: :.|..:.. |::|:.:||.|.
 Frog   437 EYYQCPLLENWEKMTDKELGKKLASLYGNDTEKLEFIPGLLAE-MAGNSINF-FSDIVLEQFYRL 499

  Fly   729 KQGDRYYYEYDNGINPGAFNPLQLQEIRKVTLARLL---CDNSDRLTLQAVPLAAFVRADHPGNQ 790
            :.|||:::|   .:..|.|:...:..||.:.|..:|   .|..|.:.....    |::.|.|
 Frog   500 RDGDRFWFE---NVKNGLFSKKDIDNIRNIKLQNVLVAVTDAGDTIQQNVF----FLKEDDP--- 554

  Fly   791 MIGCDDP-NLPSVNLE 805
               |..| .|.|..||
 Frog   555 ---CPQPKQLQSEELE 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxt	NP_650648.3	An_peroxidase	237..781	CDD:460804	143/574 (25%)
duox2	XP_017947900.2	dual_peroxidase_like	29..581	CDD:188652	152/601 (25%)
		PTZ00183	746..925	CDD:185503
		EFh	809..870	CDD:238008
		COG4097	1009..1517	CDD:443273
		NOX_Duox_like_FAD_NADP	1244..1517	CDD:99783