DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment osa and Arid4b

DIOPT Version :9

Sequence 1:	NP_001163639.1	Gene:	osa / 42130	FlyBaseID:	FBgn0261885	Length:	2716	Species:	Drosophila melanogaster
Sequence 2:	NP_919238.1	Gene:	Arid4b / 94246	MGIID:	2137512	Length:	1314	Species:	Mus musculus

Alignment Length:	312	Identity:	72/312 - (23%)
Similarity:	115/312 - (36%)	Gaps:	51/312 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   805 MPMGPPHHMGPPHGPTNMGPPTSTPPQSQMLQGGQPQGQGASGGPESGGPEHISQDNGISSSGPT 869
            :|:..|.|.|.|    .:|..|:...:|..:    |:.:.:|...:....|....|
Mouse   123 LPLTNPEHFGTP----VIGKKTNRGRRSNHI----PEEESSSSSSDDDEEERKQTD--------- 170

  Fly   870 GAAGMHAVTSVVTTGPDGTSMDEVSQQSTLSNASAASGEDPQCTTPKSRKND------------- 921
                 ..:..||       .:|.||.:...:....|....|.|:...:.|.|
Mouse   171 -----ELLGKVV-------CVDYVSLEKKKAMWFPALVVCPDCSDEIAVKKDNILVRSFKDGKFT 223

  Fly   922 --PYSQSHLAPPSTSPHP-VVMHPGGGPGEEYDMSS--PPNWPRPAGSPQVFNHVPVPQEPFRST 981
              |....|.....|.|.| .|:........|:..|.  |.||..........:.....:|  ...
Mouse   224 SVPRKDVHEITSDTVPKPDAVLKQAFDQALEFHKSRAIPANWKTELKEDSSSSEAEEEEE--EED 286

  Fly   982 ITTTKKSDSLCKLYEMDDNP-DRRGWLDKLRAFMEERRTPITACPTISKQPLDLYRLYIYVKERG 1045
            ....|:.:|..:..|::..| :|..:|.:|..|||:|.|||...|.:..:.|:|::|:..|.:.|
Mouse   287 DEKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDRGTPINKRPVLGYRNLNLFKLFRLVHKLG 351

  Fly  1046 GFVEVTKSKTWKDIAGLLGIGASSSAA-YTLRKHYTKNLLTFECHFDRGDID 1096
            ||..:.....||.:...|||...:||| |.::..|.|.|..||.:....:||
Mouse   352 GFDNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYGFEEYCRSANID 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
osa	NP_001163639.1	BRIGHT	1001..1092	CDD:128777	33/92 (36%)
osa	NP_001163639.1	DUF3518	2191..2451	CDD:288854
Arid4b	NP_919238.1	TUDOR	58..113	CDD:197660
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	123..169		11/53 (21%)
		RBB1NT	168..263	CDD:369729	19/115 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	266..306		4/41 (10%)
		ARID_ARID4B	308..399	CDD:350647	32/90 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..577
		CD_CSD	573..630	CDD:391946
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	635..678
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	709..888
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	943..1215
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1256..1290
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940