DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment osa and SWI1

DIOPT Version :9

Sequence 1:	NP_001163639.1	Gene:	osa / 42130	FlyBaseID:	FBgn0261885	Length:	2716	Species:	Drosophila melanogaster
Sequence 2:	NP_015309.1	Gene:	SWI1 / 856091	SGDID:	S000005937	Length:	1314	Species:	Saccharomyces cerevisiae

Alignment Length:	560	Identity:	108/560 - (19%)
Similarity:	181/560 - (32%)	Gaps:	181/560 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   747 TPPPPVVGGPPPPQGSGSPRPLNYLKQHLQHKGGYGGSPTPPQGPQGYGNGPTGMHPGMPMGPPH 811
            |.|..||....|...:|. :..|:::.               |.||  .|.|...:
Yeast   113 TSPTAVVNNAAPANVTGG-KAANFIQN---------------QSPQ--FNSPYDSN--------- 150

  Fly   812 HMGPPHGPTNMGPPTSTPPQSQMLQGG---------QPQGQGASGGPESGGPEHISQDNGISSSG 867
                 :..||:   .|..||:.:.:..         |.| |...||..:.....|:.||.|:...
Yeast   151 -----NSNTNL---NSLSPQAILAKNSIIDSSNLPLQAQ-QQLYGGNNNNNSTGIANDNVITPHF 206

  Fly   868 PTGAAGMHAVTSVVTTGPDGTSMDEVSQQ-----------------STLSNASAASGEDPQCT-- 913
            .|....:...:|..|...:..|....:||                 ..:||.:|::..|...:
Yeast   207 ITNVQSISQNSSSSTPNTNSNSTPNANQQFLPFNNSASNNGNLTSNQLISNYAASNSMDRSSSAS 271

  Fly   914 ---TPKSRKNDPYSQSH-----LAPPSTSPHPVVMHPGGGPGEEYDMSSPPNW---PRPA----- 962
               .|.:..|:..|.:|     ....:::.:.|...|...|....:.:|..|.   .|.|
Yeast   272 NEFVPNTSDNNNNSNNHNMRNNSNNKTSNNNNVTAVPAATPANTNNSTSNANTVFSERAAMFAAL 336

  Fly   963 -------------GSPQVFNHVPVPQEPFRSTITTTKKSDSLCKLYEMDDNPDRRGWLDKLRAFM 1014
                         ...|..|.....|:|.:.     ::.....|..:......:|..|..|...:
Yeast   337 QQKQQQRFQALQQQQQQQQNQQQQNQQPQQQ-----QQQQQNPKFLQSQRQQQQRSILQSLNPAL 396

  Fly  1015 EE------------------------RRTPITACPTISKQPLDLYRLYIYVKERGGFVEVTKSKT 1055
            :|                        |..|:.:.|.|..:.::|:.||:.|::.||..:||:::.
Yeast   397 QEKISTELNNKQYELFMKSLIENCKKRNMPLQSIPEIGNRKINLFYLYMLVQKFGGADQVTRTQQ 461

  Fly  1056 WKDIAGLLGIGASSSAAYTLRKHYTKNLLTFECHFDRGDIDPLPIIQQVEAGSKKKTAKAASVPS 1120
            |..:|..|.|    |....|...|.:.||.:|.|          :|.|  .|.|:..||...:..
Yeast   462 WSMVAQRLQI----SDYQQLESIYFRILLPYERH----------MISQ--EGIKETQAKRIFLQQ 510

  Fly  1121 PGGGHLD------------AGTTNSTGSSNSQDSFPAPPGSAPNAAIDGYPGYPGGSPYPVASGP 1173
                .|.            |...|:..:.||..|.|.|  :||.|::            |..:.|
Yeast   511 ----FLQELLKKVQQQQQAAALANANNNINSASSAPTP--AAPGASV------------PATAAP 557

  Fly  1174 QPDYATAGQMQRPPSQNNPQTPHPGAAAAVAAGDNISVSN 1213
            ..:   ||.:  |.|.|.|:        ::.:..||:|:|
Yeast   558 GTE---AGIV--PVSANTPK--------SLNSNININVNN 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
osa	NP_001163639.1	BRIGHT	1001..1092	CDD:128777	27/114 (24%)
osa	NP_001163639.1	DUF3518	2191..2451	CDD:288854
SWI1	NP_015309.1	ARID_Swi1p-like	407..490	CDD:350635	21/86 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030