DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment osa and ARID4A

DIOPT Version :9

Sequence 1:	NP_001163639.1	Gene:	osa / 42130	FlyBaseID:	FBgn0261885	Length:	2716	Species:	Drosophila melanogaster
Sequence 2:	XP_016877049.1	Gene:	ARID4A / 5926	HGNCID:	9885	Length:	1284	Species:	Homo sapiens

Alignment Length:	240	Identity:	58/240 - (24%)
Similarity:	85/240 - (35%)	Gaps:	81/240 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   849 PESGGPEHISQDNGISSSGPTGAAGMHAVTSVVTTGPDGTSMDEVSQQSTLSNASAASGEDPQCT 913
            |||    .:|...|:..      |.:...|.||   ||...||    .|.:..:|::..||
Human   238 PES----ELSTKPGLQK------ASIFLKTRVV---PDNWKMD----ISEILESSSSDDED---- 281

  Fly   914 TPKSRKNDPYSQSHLAPPSTSPHPVVMHPGGGPGEEYDMSSPPNWPRPAGSPQVFNHVPVPQEPF 978
                                           ||.||.|........:        ....||:|
Human   282 -------------------------------GPAEENDEEKEKEAKK--------TEEEVPEE-- 305

  Fly   979 RSTITTTKKSDSLCKLYEMDDNPDRRGWLDKLRAFMEERRTPITACPTISKQPLDLYRLYIYVKE 1043
                             |:|.. :|..:|.:|..|||:|.|||...|.:..:.|:|::|:..|..
Human   306 -----------------ELDPE-ERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYH 352

  Fly  1044 RGGFVEVTKSKTWKDIAGLLGIG-ASSSAAYTLRKHYTKNLLTFE 1087
            :||...:.....||.|...|||. .:|:|:|.::..|.|.|..||
Human   353 QGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFE 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
osa	NP_001163639.1	BRIGHT	1001..1092	CDD:128777	31/88 (35%)
osa	NP_001163639.1	DUF3518	2191..2451	CDD:288854
ARID4A	XP_016877049.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940