DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment osa and Arid3c

DIOPT Version :9

Sequence 1:	NP_001163639.1	Gene:	osa / 42130	FlyBaseID:	FBgn0261885	Length:	2716	Species:	Drosophila melanogaster
Sequence 2:	NP_001167452.1	Gene:	Arid3c / 502946	RGDID:	1560943	Length:	410	Species:	Rattus norvegicus

Alignment Length:	603	Identity:	138/603 - (22%)
Similarity:	191/603 - (31%)	Gaps:	251/603 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   818 GPTNMGPPTSTPPQSQMLQGGQPQGQGASGGPESGGPEHISQDNGISSSGPTGAAGMHAVTSVVT 882
            ||  :.||....||..:|        ||.                 :...|.||.|:     |..
  Rat    17 GP--LAPPRLPLPQPPLL--------GAR-----------------TLQAPEGALGV-----VGA 49

  Fly   883 TGPDGTSMDEVSQQSTLSNASAASGEDPQCTTPKSRKNDPYSQSHLAPPSTSPHPVVMHPGGGPG 947
            ...:|...||             .||.|..      :.:...|||                  ||
  Rat    50 EEEEGAEEDE-------------EGETPLV------EEETAEQSH------------------PG 77

  Fly   948 EEYDMSSPPNWPRPAG-SPQVFNHVPVPQEPFRSTITTTKKSDSLCKLYEMDDNPDRRGWLDKLR 1011
                 :..||  .|:| ||.:..|....:|.|:             :|||:|.:|.|:.:||.|.
  Rat    78 -----ARCPN--SPSGQSPGIQPHEWTYEEQFK-------------QLYELDADPKRKEFLDDLF 122

  Fly  1012 AFMEERRTPITACPTISKQPLDLYRLYIYVKERGGFVEVTKSKTWKDIAGLLGIGAS-SSAAYTL 1075
            :||::|.||:...|.::||.||||.|:..|..:||.|||...|.|:::...|.:..: :|||:||
  Rat   123 SFMQKRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTL 187

  Fly  1076 RKHYTKNLLTFECHFDRGDIDPLPIIQQVEAGSKKKTAKAASVPSPGGGHLDAGTTNSTGSSNSQ 1140
            |..|.|.|..:||.                       .:|.|.|    |.|.|..     .||.:
  Rat   188 RTQYMKYLYPYECE-----------------------TRALSSP----GELQAAI-----DSNRR 220

  Fly  1141 DSFPAPPGSAPNAAIDGYPGYPGGSPYPVASGPQPDYATAGQMQRPPSQNNPQTPHPGAAAAVAA 1205
            :                              |.:..|.|....       |...|.|..|.
  Rat   221 E------------------------------GRRQAYTTVPLF-------NLAGPTPRGAP---- 244

  Fly  1206 GDNISVSNPFEDPIAAGGGPGSGTGPGPGQGPG-PGAASGGAGAVGAVGGGP-QPHP-------- 1260
                              ||.|..||.|...|. ||:..|.|..:.|..... .|.|
  Rat   245 ------------------GPASSHGPAPTTTPNCPGSTQGSASGLPAHACAQLSPSPVKKEESGI 291

  Fly  1261 PPPH--SPHTAAQQAAGQHQQQHPQHQHPGLPGPPPPQQQQGQQGQQPPPSVGGGPPPAPQQHGP 1323
            |||.  .|...|.:||  .::..|:.         ||:::....|...||.:|..|...|:
  Rat   292 PPPRLAIPVGLALEAA--REKLAPEE---------PPEKRAVLMGPMDPPRLGATPSFLPR---- 341

  Fly  1324 GQVPPSPQQHVRPAAGAPYPPGGSG-----------------------YPTPVSRTPGSPYPSQP 1365
            |:.|...::     ...|....|||                       .|.|.|..|.:| |..|
  Rat   342 GKAPLREER-----LDGPLNLAGSGISSINMALEINGVVYTGILFARRQPVPASLGPTNP-PPPP 400

  Fly  1366 GAYGQYGSSDQYNATGPP 1383
                         :||||
  Rat   401 -------------STGPP 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
osa	NP_001163639.1	BRIGHT	1001..1092	CDD:128777	38/91 (42%)
osa	NP_001163639.1	DUF3518	2191..2451	CDD:288854
Arid3c	NP_001167452.1	BRIGHT	112..203	CDD:128777	38/113 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.870