Protein Alignment osa and arid3a

DIOPT Version :9

• Sequence 1: NP_001163639.1
• Gene: osa / 42130
• FlyBaseID: FBgn0261885
• Length: 2716
• Species: Drosophila melanogaster
• Sequence 2: NP_001011106.1
• Gene: arid3a / 496519
• XenbaseID: XB-GENE-945264
• Length: 541
• Species: Xenopus tropicalis
• Alignment Length: 540
• Identity: 132/540 - (24%)
• Similarity: 192/540 - (35%)
• Gaps: 137/540 - (25%)

  Fly   831 QSQMLQGGQPQGQGASG-GPESGGPEHISQDNGISSSGPTGAAGMHAVTSVVTTGPDGTSMDE-- 892
            |....:|..|...|..| |.|...||.:.    |..:.....|.|.|..:.::..|...:.||
 Frog    28 QQDSSEGRTPPSVGYPGNGSEEAEPEALK----IQRAQAAALAAMRAAAAGLSQQPSPAASDEEE 88

  Fly   893 ---VSQQSTLSNASAASGEDPQCTTPKSRKND---PYSQSHLAPPSTSPHPVVMHPGGGPGEEYD 951
               .|..|...:.....||..:.....|.:.|   .:.:..............|..|.|..|...
 Frog    89 EDGESMASDEEDEKERDGESERYPDMGSEEEDLKGKWDEDDFEDEGEEDDYEDMEEGMGVSEAGR 153

  Fly   952 MSS----PPNWPRP------------------AGSPQVFNHVP-VPQEPFRSTITTTKKSDSLCK 993
            :..    ||..|.|                  .|.||:.:|.. ..:|.|:             :
 Frog   154 VGKGSTLPPKHPNPQAFPTQRSVGAERAGLPHTGHPQLQDHGDWTYEEQFK-------------Q 205

  Fly   994 LYEMDDNPDRRGWLDKLRAFMEERRTPITACPTISKQPLDLYRLYIYVKERGGFVEVTKSKTWKD 1058
            |||:|.:|.|:.:||.|.:||::|.||:...|.::||.||||.||:.|.|:||.|||...|.|::
 Frog   206 LYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLYMLYVLVTEKGGLVEVINKKLWRE 270

  Fly  1059 IAGLLGIGAS-SSAAYTLRKHYTKNLLTFECHFDRGDIDPLPIIQQVEA----GSKKKTAKAASV 1118
            |...|.:..| :|||:|||..|.|.|..:||. .||..:|..:...:::    |.::....:...
 Frog   271 ITKGLNLPTSITSAAFTLRTQYMKYLYPYECE-KRGLSNPNELQAAIDSNRREGRRQSFGGSLFT 334

  Fly  1119 PSPGG------------GHLDAGTTNSTGSS-----------NSQDSFPAPPG------------ 1148
            .||.|            ..|..|...:.|||           :|..|...||.
 Frog   335 YSPSGAPSMLSSPKLQVSALSLGGVATNGSSLSSMQKIKKEEDSPISLTVPPRIPVSLAGHSMVA 399

  Fly  1149 ---SAPNAAIDGYPGYPGGSPYPVASGPQPDYATA------GQMQRPPSQN----NPQTP----- 1195
               :|..||::..       ...:.||..|:...|      .::||....|    ..|.|
 Frog   400 AQVAAQAAALEQL-------REKLESGEPPEKKMALGTEEQQRLQRAIQHNLLAMTAQLPMNIRI 457

  Fly  1196 -------HPGAAAAVAAGDN-ISVSNPFEDPIAAGGGPGSGTGPGPGQGP--GPGAASGGAGAVG 1250
                   ...|......|.| ||:|......:.        ||....|.|  ..|.:.|.:...|
 Frog   458 NSQAEGRQDSAVNLTTNGTNSISMSVELNGIVY--------TGVLFAQPPTSASGTSKGSSNRTG 514

  Fly  1251 AVGGG---PQPHPPP-PHSP 1266
            ::|||   .|..||| |.:|
 Frog   515 SIGGGSSTSQAAPPPAPSAP 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osa	NP_001163639.1	BRIGHT	1001..1092	CDD:128777	42/91 (46%)
		DUF3518	2191..2451	CDD:288854
arid3a	NP_001011106.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	17..172		30/147 (20%)
		ARID_ARID3A	193..325	CDD:350642	53/145 (37%)
		Important for nuclear localization. /evidence=ECO:0000250	408..450		8/48 (17%)
		Homodimerization. /evidence=ECO:0000250	452..473		2/20 (10%)
		Important for cytoplasmic localization. /evidence=ECO:0000250	497..504		2/6 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	499..541		13/36 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940