Protein Alignment osa and arid4a

DIOPT Version :9

• Sequence 1: NP_001163639.1
• Gene: osa / 42130
• FlyBaseID: FBgn0261885
• Length: 2716
• Species: Drosophila melanogaster
• Sequence 2: XP_005158686.1
• Gene: arid4a / 327404
• ZFINID: ZDB-GENE-050809-105
• Length: 1332
• Species: Danio rerio
• Alignment Length: 1278
• Identity: 238/1278 - (18%)
• Similarity: 391/1278 - (30%)
• Gaps: 421/1278 - (32%)

  Fly   972 PVPQEPFRSTITTTKKSDSLCKLYEMDDNPD---RRGWLDKLRAFMEERRTPITACPTISKQPLD 1033
            |.|:||                    ||.||   |..:|.:|..|||:|.|||...|.:..:.|:
Zfish   297 PEPEEP--------------------DDEPDPEERDHFLQQLYKFMEDRGTPINKPPVLGYKDLN 341

  Fly  1034 LYRLYIYVKERGGFVEVTKSKTWKDIAGLLGIGA-SSSAAYTLRKHYTKNLLTFE--C------- 1088
            |::|:..|...||...:.....||.|...|||.. :|:|:|.::..|.|.|..||  |
Zfish   342 LFKLFRLVHIHGGCDNIESGSIWKQIYMDLGIPVLNSAASYNVKTAYRKYLYGFEEYCRSAQIQF 406

  Fly  1089 ---HFDRGDIDPLPIIQQVEAGSKKKTAKAASVPSPGGGHLDAGTTNSTGSSNSQDSFPAPPGSA 1150
               |.:....|..|.:|.:::.:|:         |.....:....|...|:|..:     |...|
Zfish   407 RTVHHNEPRPDVQPEVQSIKSVTKE---------SENNDEMMQQVTAEPGTSEDK-----PAADA 457

  Fly  1151 PNAAIDGYPG-----YPGG------SPYPVASGP-----------QPDYATAGQM--QRPPSQNN 1191
            ..:..:...|     .|.|      :|..|...|           :.|..:.|:.  :.|..:::
Zfish   458 DESDAESEKGRKDVCSPRGRRRCLTTPVKVEMEPLKQEKIKEEKKKEDTQSVGENSGEEPKEKSD 522

  Fly  1192 PQTPHPGAAAAVAAGDNISVSNP-----------------------------FEDPIAAGGGPGS 1227
            .:.|....:......|..|..:.                             ||         .|
Zfish   523 GEIPGKRRSRRHEESDKDSEEDDDDNDDEEQDDDDEDDEEEEEDDDDEEEDYFE---------RS 578

  Fly  1228 GTGPGPGQGPGPGAASGGAGAVGA-----VGGGPQPHPPPPHSPHTAAQQA-------------- 1273
            .......:..|.|.........|.     .|.|........:..:|.....
Zfish   579 RLRERDEREEGDGCEDSEHSLAGTKVRVKYGKGKTQKIYEANIKNTETDDGEVLYLVHYYGWNVR 643

  Fly  1274 ----------------AGQHQQQHPQHQHPGLPGPPPPQQQQGQQGQQPPPSV----GGGP---- 1314
                            .|..::|..:.::         ::.:.::.::....|    |..|
Zfish   644 YDEWVKADRIIWPVDKGGTKKKQKKKVKN---------KEDEEKEKEEDKTKVVVRRGRPPLKST 699

  Fly  1315 PPAPQQHGPGQVPPSPQQHVRPAAGAPYPPGGSGYPTPVSRTPGSPYPSQPGAYGQYGSSDQYNA 1379
            ||...:..|.....|..::.|| ..|...|.|.|.|...:|.....|.|..|:.....|||....
Zfish   700 PPGTSRKTPSSEGRSSSKNSRP-TDASALPNGDGTPRRRTRRTSGMYDSDRGSNDSGNSSDDSEG 763

  Fly  1380 -------------TGPPGQPFG-QGPGQYPPQNRNMYPPYGPEGEAPPTGANQYGPYGSRPYSQP 1430
                         |.||  |.. |......|:......|...|.|.|  .:.|..|..:...|:|
Zfish   764 EKSPEKKQEWTERTDPP--PIAKQEAADDLPEESTTQEPAQTEPELP--SSPQEMPNFNESESKP 824

  Fly  1431 PPGGPQPPTQTVAGGP------PAGGAPGAPPSSAYPTGRPSQQDYYQPPPDQSPQPRRHPDFIK 1489
            ......|||::..|.|      |....||    |..||..|:..:::....:.|..||.    :|
Zfish   825 EEDSSMPPTESDVGSPKMTAKKPRLKEPG----SETPTQTPAAANHHAETEEPSTPPRP----VK 881

  Fly  1490 DSQPYPGYNARPQIY------GAWQSGTQQYRPQYPSSPAPQNWGGAPPRGAAPPPGAPHGPPIQ 1548
            .||..|..:...:|.      ....|.|:...|...:|.|.:.....                 :
Zfish   882 KSQETPHSSPVERIKLVETAGSDTDSATEDIDPPERTSAAKRKINEQ-----------------R 929

  Fly  1549 QPAGVAQWDQHRYPPQQGPPPPPQQQQQPQQQQQQPPYQQVAGPPGQQPPQAPPQWAQMNPGQTA 1613
            .|....:.|:...|....|......:::|:.:::....|:         |:.||     ||
Zfish   930 TPEKKIRLDRKEEPKTPSPVKTSPLEKKPESEKRTEIVQK---------PEEPP-----NP---- 976

  Fly  1614 QSGIAPPGSPLRPPSGPGQQNRMPG-MPAQQQQSQQQGGVPQP----PPQQASHGGVPSPGLPQV 1673
                        ..|.|.::..:.. ||:..::...:...|.|    |...|:     ...:||:
Zfish   977 ------------TLSSPSKEVEIKSEMPSLTREVHLKLEAPCPDLEDPTTVAN-----EEMMPQI 1024

  Fly  1674 GPGGMVKPPYAMPPP-----PSQGVGQQVGQGPPGGMMSQKPPPMPGQAMQQQPLQQQPPSHQHP 1733
            ||..:|.....:..|     ||                |::.|.|..:.:..|||:.
Zfish  1025 GPEALVCHEVDLDDPEEKDKPS----------------SEELPIMKEEKVLPQPLES-------- 1065

  Fly  1734 HPHQHPQHQH--PHQMPPNQTAPGGYGPPGMPGGGAQLVKKELIFPHDSVESTTPVLYRRKRLMK 1796
                 |.|.|  |...||...:|.....|                  |...||           |
Zfish  1066 -----PDHLHVLPAVGPPRLFSPSSAPSP------------------DESHST-----------K 1096

  Fly  1797 ADVCPVDPWRIFMAMRSGLLTECTWALDVLNVLLFDDSTVQFFGISNLPGLLTLLLEHFQKNLAE 1861
            ::                                 .|:|::...::           ..|:.|.|
Zfish  1097 SE---------------------------------SDATIEVDSVA-----------ESQEGLGE 1117

  Fly  1862 -----MFDERENEEQSALLAEDADDDADSGTVMCEKLRTSGRQPRCVRSISSYNRRRHYENMD-- 1919
                 .||...:...|::..:|.|.          |.|...|...|....||..::|..:...
Zfish  1118 NESTHSFDASASSSNSSISLQDRDG----------KDRGQKRLLDCTTVSSSKKQKRSQKRSSVG 1172

  Fly  1920 -RSGKDGAGNGSDSEDADEGIDLGQVRVQPNPEERSLLLSFTPNYTMVTRKGVPVRIQPAENDIF 1983
             ::.|:|||:.||||  |:.:..|..::  .|.:.|:|    |....::|.  |....|:...|.
Zfish  1173 CKTEKNGAGHSSDSE--DQSVMDGSNKL--TPVKHSIL----PKNQKLSRS--PGLGSPSNKYIE 1227

  Fly  1984 VDERQKAWDIDTNRLYEQLEPVGSDAWTYGFTEPDPLDGI--IDVFKSEIVNIPFARYIRSDKKG 2046
            .|:.::...:.:.|.|:         |:...||.|.:...  |...:.::..|  .:|..|.|
Zfish  1228 KDKHKEKQSVPSPRTYK---------WSCQLTELDNMSSAERISFLQDKLQEI--RKYYMSLK-- 1279

  Fly  2047 RKRTELAS-SSRKPEIKTEENSTEEQTFNKKRRLVSGGSSSSG 2088
               :|:|| ..|:..:|.:|......|.:     .|.|||.:|
Zfish  1280 ---SEVASIDRRRKRLKKKEREVSHTTAS-----TSSGSSDTG 1314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osa	NP_001163639.1	BRIGHT	1001..1092	CDD:128777	35/106 (33%)
		DUF3518	2191..2451	CDD:288854
arid4a	XP_005158686.1	TUDOR	58..113	CDD:295375
		RBB1NT	171..260	CDD:285392
		ARID	311..396	CDD:198082	29/84 (35%)
		Tudor-knot	601..654	CDD:288553	4/52 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940