DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment osa and cfi-1

DIOPT Version :9

Sequence 1:	NP_001163639.1	Gene:	osa / 42130	FlyBaseID:	FBgn0261885	Length:	2716	Species:	Drosophila melanogaster
Sequence 2:	NP_492644.2	Gene:	cfi-1 / 188793	WormBaseID:	WBGene00000476	Length:	467	Species:	Caenorhabditis elegans

Alignment Length:	340	Identity:	83/340 - (24%)
Similarity:	125/340 - (36%)	Gaps:	112/340 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   820 TNMGPPTSTPPQSQMLQGGQPQGQGASGGPESGGPEHISQD-NGISSSGPTGAAGMHAVTSVVTT 883
            :|:..|.:.||..|.||                ||..|.|. .|:       |:|:.|::
Worm    83 SNLRAPLNLPPIFQALQ----------------GPFSIQQQLLGL-------ASGLTAIS----- 119

  Fly   884 GPDGTSMDEVSQQSTLSNASAASGEDPQCTTPKSRKNDPYSQSHLAPPSTSPHPVVMHPGGGPGE 948
                ..:|:..:::|      ..||....|....||........                  |.|
Worm   120 ----PGLDDYDEENT------NQGEPEDLTLGGFRKETSVKSEE------------------PSE 156

  Fly   949 EYDMSSPPNWPRPAGSPQVFNHVPVPQEPFRSTITTTKKSDSLCKLYEMDDNPDRRGWLDKLRAF 1013
            ....:|.|.|..              :|.|:             :|||:.|:..|:.|||....|
Worm   157 SGINASGPAWSY--------------EEQFK-------------QLYELSDDVKRKEWLDDWLNF 194

  Fly  1014 MEERRTPITACPTISKQPLDLYRLYIYVKERGGFVEVTKSKTWKDIAGLLGIGAS-SSAAYTLRK 1077
            |.....|:|..|.::||.||||.||..|.:.||.||:...|.|::|...|.:.:| :|||:|||.
Worm   195 MHRIGKPVTRIPIMAKQVLDLYELYRLVVQHGGLVEIINKKLWREITKGLNLPSSITSAAFTLRT 259

  Fly  1078 HYTKNLLTFECHFDRGDIDPLPIIQQVEAGSKKKTAKAASVPSPGGGHLDAGTTNSTGSSNSQDS 1142
            .|.|.|..:||  ::..:.....:||...|::::.....:.|                      |
Worm   260 QYQKYLYDYEC--EKEKLSNQSDLQQAIDGNRREAPGRRTAP----------------------S 300

  Fly  1143 FPAP---PGSAPNAA 1154
            ||.|   |.:|..||
Worm   301 FPLPFQLPHAASAAA 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
osa	NP_001163639.1	BRIGHT	1001..1092	CDD:128777	38/91 (42%)
osa	NP_001163639.1	DUF3518	2191..2451	CDD:288854
cfi-1	NP_492644.2	ARID	183..269	CDD:198082	36/85 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.900