Protein Alignment osa and ARID3B

DIOPT Version :9

• Sequence 1: NP_001163639.1
• Gene: osa / 42130
• FlyBaseID: FBgn0261885
• Length: 2716
• Species: Drosophila melanogaster
• Sequence 2: NP_001294868.1
• Gene: ARID3B / 10620
• HGNCID: 14350
• Length: 561
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 126/475 - (26%)
• Similarity: 168/475 - (35%)
• Gaps: 130/475 - (27%)

  Fly   814 GPPHGPTNMGPPTSTPPQSQMLQGGQPQGQGASGGPESGGPEHISQDNGIS--SSGPTGAAGMH- 875
            |.|.|.|.:||....||.:.:.|..:.....:....|.||.|....|:.::  :...|.||..:
Human    58 GRPSGSTPLGPLARVPPTAAVAQVFERGNMNSEPEEEDGGLEDEDGDDEVAEVAEKETQAASKYF 122

  Fly   876 AVTSVVTTGPDGTSMDEVSQQSTLSNASAASGEDPQCTTPKSRKNDPYSQSHLAPPSTSPHPVVM 940
            .|..|....|         :.:.:||...|.|..|.   .:..|.|....:..|.||.|
Human   123 HVQKVARQDP---------RVAPMSNLLPAPGLPPH---GQQAKEDHTKDASKASPSVS------ 169

  Fly   941 HPGGGPGEEYDMSSPPN----WPRPAGSPQVFNHVPVPQEPFRSTITTTKKSDSLCKLYEMDDNP 1001
             ..|.|....|.....|    |...|...:                 ..:.|....||||:|.:|
Human   170 -TAGQPNWNLDEQLKQNGGLAWSDDADGGR-----------------GREISRDFAKLYELDGDP 216

  Fly  1002 DRRGWLDKLRAFMEERRTPITACPTISKQPLDLYRLYIYVKERGGFVEVTKSKTWKDIAGLLGIG 1066
            :|:.:||.|..||::|.|||...|.::||.||||.||..|.|:||.||:...|.|::|...|.:.
Human   217 ERKEFLDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLP 281

  Fly  1067 AS-SSAAYTLRKHYTKNLLTFECHFDRGDIDPLPIIQQVEAGSKKKTAKAASVPSPGGGHLDAGT 1130
            .| :|||:|||..|.|.|..:||.                       .||.|.|
Human   282 TSITSAAFTLRTQYMKYLYAYECE-----------------------KKALSSP----------- 312

  Fly  1131 TNSTGSSNSQDSFPAPPGSAPNAAIDGYPGYPGGSPYPVASGPQPDYATAGQMQRPPSQNNPQTP 1195
                              :...|||||..          ..|.:|.|:::.....|.:
Human   313 ------------------AELQAAIDGNR----------REGRRPSYSSSLFGYSPAA------- 342

  Fly  1196 HPGAAAAVAAGDNISVSNP-FEDPIAAGGGPGSGTG-PGPGQGPGPGAASGGAGAVGAVGGGPQP 1258
               |.||.|||....:|.| ...|| .|.|..|||. ..|...|......|        .|.|..
Human   343 ---ATAAAAAGAPALLSPPKIRFPI-LGLGSSSGTNTSSPRISPATTLRKG--------DGAPVT 395

  Fly  1259 HPPPPHS---PHTAAQQAAG 1275
            ..|.|:.   |.|.|.|.||
Human   396 TVPVPNRLAVPVTLASQQAG 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osa	NP_001163639.1	BRIGHT	1001..1092	CDD:128777	42/91 (46%)
		DUF3518	2191..2451	CDD:288854
ARID3B	NP_001294868.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	53..122		17/63 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..179		13/52 (25%)
		Interaction with RB1. /evidence=ECO:0000269|PubMed:10446990	203..365		71/234 (30%)
		BRIGHT	216..305	CDD:128777	41/88 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	370..397		8/34 (24%)
		Interaction with ARID3A. /evidence=ECO:0000269|PubMed:17400556	490..513
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	523..561

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.900