DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31249 and RTRAF

DIOPT Version :9

Sequence 1:	NP_732262.1	Gene:	CG31249 / 42129	FlyBaseID:	FBgn0051249	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_057123.1	Gene:	RTRAF / 51637	HGNCID:	23169	Length:	244	Species:	Homo sapiens

Alignment Length:	230	Identity:	91/230 - (39%)
Similarity:	136/230 - (59%)	Gaps:	11/230 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DRKEFANTVLWLEDQKIRLYSIEDRCKLRTVDNPEIWKEGYLKYCADLSMP-PLETRQEQLAWIV 87
            |..||.|.::||||||||.|.||||..||.:.:.: |.:.:.||..|::.| .::.|||.:.|::
Human    21 DETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSD-WPKFFEKYLRDVNCPFKIQDRQEAIDWLL 84

  Fly    88 SYAVRLDFLDDPDQFASINTKQVPPQS-NGKQSQQRVQAIFDGNINTQEKAFVDGVRLLASKLNV 151
            ..||||::.|:.:::..:    ||..| ....:.:..:.:.:.::|..:  |..||..||:.|.:
Human    85 GLAVRLEYGDNAEKYKDL----VPDNSKTADNATKNAEPLINLDVNNPD--FKAGVMALANLLQI 143

  Fly   152 PHHPNHLLQLEAIARVVHERLS--PAAKDRKPVVGKPFPFDKGNDVVSSNDSALDLPMRILRLLQ 214
            ..|.::|:.|:||..:|.|||:  ..||..:...|.|...||......:.|:.|:...:|||||.
Human   144 QRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALDKHILGFDTGDAVLNEAAQILRLLH 208

  Fly   215 IQSLRELQTHINETIVAVQNITANPKTDTKLGKVG 249
            |:.||||||.|||.|||||.|.|:||||.:|||||
Human   209 IEELRELQTKINEAIVAVQAIIADPKTDHRLGKVG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31249	NP_732262.1	RLL	7..249	CDD:287054	89/228 (39%)
RTRAF	NP_057123.1	RLL	8..243	CDD:401864	89/228 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150740
Domainoid	1	1.000	148	1.000	Domainoid score	I4494
eggNOG	1	0.900	-	-		E1_KOG4380
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9355
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4409
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59794
OrthoDB	1	1.010	-	-		D1239557at2759
OrthoFinder	1	1.000	-	-		FOG0005794
OrthoInspector	1	1.000	-	-		oto88618
orthoMCL	1	0.900	-	-		OOG6_105549
Panther	1	1.100	-	-	LDO	PTHR15924
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2943
SonicParanoid	1	1.000	-	-		X5512
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800