Protein Alignment alt and ktn1

DIOPT Version :10

• Sequence 1: NP_650645.1
• Gene: alt / 42127
• FlyBaseID: FBgn0038535
• Length: 874
• Species: Drosophila melanogaster
• Sequence 2: NP_001296258.1
• Gene: ktn1 / 368207
• ZFINID: ZDB-GENE-030408-4
• Length: 1262
• Species: Danio rerio
• Alignment Length: 1040
• Identity: 227/1040 - (21%)
• Similarity: 406/1040 - (39%)
• Gaps: 293/1040 - (28%)

  Fly    48 KAAGGAATKKPKKKELKREKKQRQREQQRDVNNEPEP-----EEAEDYSDGQSEGQGSVAGEEPG 107
            ||:..|.::...||:.|::|.:.: |...:|..:|.|     ||.........:|...|:...|.
Zfish   194 KASPPAPSETTSKKKAKKQKSEAE-EHAPEVKPDPSPPVVKKEEPVITEVKTQDGAAPVSTAAPP 257

  Fly   108 LS---------KQHVEFEPDAEVLTDQRRPSSVA------------EKENQ----------PSGA 141
            .:         ||.||    |.|..|:....|.|            .:.||          |:..
Zfish   258 TASSSSGRRKKKQKVE----AAVTVDEAHVQSSALVIQIGSAAPTNHQNNQNNDTPPPVPAPAKH 318

  Fly   142 GKKGKKDKRNGANNKT---------AGILVNKNETVAVKPAANAEETPTLNNFETKIPKDVVELK 197
            ||| :|.:.|..|::.         .|::::.::.|::......:....|:|:.    |...:.:
Zfish   319 GKK-QKSETNKENSEVKLKELLASIGGLVLSDSDVVSLVSLLREKSPNALDNWY----KSTAKFE 378

  Fly   198 KQEQKERKEDN-NNKQQSQKKIAGGNV--------SKKEKVVAVET------------------- 234
            ...|:..::|. .|..|.:..||.|.|        ::|:|...||:
Zfish   379 PTPQQLAEKDRLLNTLQEEASIAKGKVKQLSQELQAEKQKTGRVESVLHEHRVARDKDIMQAKAQ 443

  Fly   235 ---EAPVVTKQILKQ------QQQQQNGSPKTQHNQANN----KTKQQQQ-NKKQNQKETLTGKD 285
               |..:..:||.:|      :.||:||..:....:.:.    :|||..: ||.:::..:|. |:
Zfish   444 SYQEMQIKFQQIREQLDGQIARLQQENGILRDAVERCSTTNQMETKQSSELNKLRSEYNSLM-KE 507

  Fly   286 LAHALDKLADHQNQTIGV----------------------NALMNVFSRAELNRSEI--QILI-- 324
            ||...:||...:.|..|:                      |.|.:|.:..|..:||:  ||::
Zfish   508 LAETKNKLQQEELQRKGLEVNYKQNVSQLEDAKHRWEDLQNYLHSVNAEREKIQSELQNQIMVAE 572

  Fly   325 DYLLNKQQDMPASHSEWSDDICQKLKRQLEEKEKLLAEEQEASIGIQAKLRELRQEVNTERAQMH 389
            ..:.:|.:::.:.||...|.:..|    .:|::|:|..||:....::|..|.::.:
Zfish   573 SEMASKNKEIQSLHSSLKDTLMFK----DQEQQKVLQLEQQVRQLLEASQRSMQPD--------- 624

  Fly   390 ARNQAYIDKLQGKEQELAALNQELSSLNDKLTLERQQLTTLRREKQANSQDLVQLQHLQQDLAHK 454
                   |:||.|.|:|         ||:..|| :.|:..|:.:....:..:...:.||:.||.|
Zfish   625 -------DQLQEKVQDL---------LNENKTL-KVQIDNLQTQLNTQATTVSHFEELQKLLAEK 672

  Fly   455 E---KCL-----AEMTAFVNAET-----QQKNEVIQQQAQQLQA-------------LELQREEL 493
            |   |.|     ||.::..:.||     ..:|..::.:.|.|||             ..||:.:.
Zfish   673 ELQRKSLEDSLNAERSSGASRETNMQAMHNENHTLKAELQNLQAQISEKVVSVDQLQQSLQKRDE 737

  Fly   494 EARQNNSIFEL---------EQRKQLEAENADLKQELSAVQQTQSELQRVHAAELQELRQNLSVL 549
            :.|...::.|.         ::.|.:..|...|||:|.|||:..:| |.|....|:||:  |.:.
Zfish   738 KTRTVENLLETSLIQVANKEDELKVVRNECEGLKQQLEAVQKQTTE-QTVSEKALEELQ--LKIQ 799

  Fly   550 EARNVALSQQLTQAANSAVQATAAQSEQAQVQTEALAQKQQ----ELSALRSQVGS------LTD 604
            |.     .:|:.....|...|...:||:.:| .|.|.|:.:    ||:.|::|..:      |.:
Zfish   800 EK-----DEQIKSVEGSLQLAVNKESERKKV-VEDLQQQVEVLTAELAHLKTQESNSDLSAKLQE 858

  Fly   605 AHAQ---QQKQANALQSQLQEAQQRAEQ-------------LQAKEQHL---QQELQEQRE---- 646
            .|||   :.:....||.:|::..|..:|             |..|::.|   |:||.|.||
Zfish   859 LHAQLTAKDQDVERLQRELEKEMQPKQQTVSAAPSQELLTALAEKDKRLSDVQEELLELRESVEL 923

  Fly   647 ---KNNDVRMKNWKLIEALQNAEALTAKTKTNSA-------QSV-------------------GQ 682
               |||::|.|||..:|||...|.:.....|.||       :||                   .|
Zfish   924 HRKKNNELREKNWSAMEALSATETILQGKLTKSAKEHQTVLESVEAECRALLHRLLPHIPLPSDQ 988

  Fly   683 QHKELQLQQQKAVAANGGGSASSAKSEQQRIRDLYQRLYPDAVKAQSGNALQASFDQW------- 740
            .|::...:.:.:|..:..|.|||..::.     |.::| .:|.:||  ..||...:.:
Zfish   989 NHQQWVQKFEASVRESSSGEASSGDAQA-----LAEKL-KEAEEAQ--KVLQKDCETYKKVLAET 1045

  Fly   741 --LEQVLATHVKQQQDKLRQKLDAEKSEKQSSSSHKSTQSSNSSSSNHNSTHNNISSNNSSSNSQ 803
              :.|.|.:.|:.::.:.|:|||..::|.:..:...............::...::..:.....|:
Zfish  1046 EGILQRLQSSVEHEETRWREKLDLSQAELKEMTQRAIALDQEVDRLTSDADVESLRRDKQQLESE 1110

  Fly   804 SSSAAEQQELHKQNLQLRECNDKLTQLVTKTTNTLMDLEERAREQDEHWRGIVEQKEQLILTLQQ 868
            ...|..:...:..  ::||..|.||:|.:|.              |..:...|.|.|:|.|...|
Zfish  1111 LERAERESATYVS--EVRELKDLLTELQSKL--------------DGSYTEAVRQNEELNLLKTQ 1159

  Fly   869  868
            Zfish  1160  1159

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alt	NP_650645.1	Smc	<370..>633	CDD:440809	75/323 (23%)
		Smc	<530..>822	CDD:440809	79/362 (22%)
ktn1	NP_001296258.1	Rib_recp_KP_reg	31..>123	CDD:461548
		SMC_prok_B	<382..741	CDD:274008	84/389 (22%)
		Smc	629..>1236	CDD:440809	132/574 (23%)