Protein Alignment Mps1 and TTBK2

DIOPT Version :9

• Sequence 1: NP_001262677.1
• Gene: Mps1 / 42126
• FlyBaseID: FBgn0000063
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: XP_005254228.1
• Gene: TTBK2 / 146057
• HGNCID: 19141
• Length: 1250
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 58/252 - (23%)
• Similarity: 99/252 - (39%)
• Gaps: 51/252 - (20%)

  Fly   412 YMVMEKGDCDLNKILQSYTT-NLPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMVSGRLK 475
            |:||:....:|..:.:|.:. ...:.:.:.:..|:|:::..||..|.:|.|:||:||.|  ||..
Human    97 YVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAM--GRFP 159

  Fly   476 -------LIDFGIASNIAVDSTSIIKFSQA-----GTFNYISPEALTDTSTGNSPMRRADQPKIK 528
                   ::|||:|... .:|...::..:|     ||..|.|..|     ..|..|.|.|
Human   160 STCRKCYMLDFGLARQF-TNSCGDVRPPRAVAGFRGTVRYASINA-----HRNREMGRHD----- 213

  Fly   529 ISTKSDVWSLGCILYLLLYQKTPFGHIRNVYAKMSAITTPGTSIEYPAIPPYYPIMLVHFTTVSA 593
                 |:|||..:|...:..:.|:..|::.....|........:....:||.:.|.|.|.:::..
Human   214 -----DLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDY 273

  Fly   594 LFADGQELPT------------VESQ--------KAAVVHRTTTVPIPYDHSAAEPA 630
            ......:|.|            :||.        ....:..|||...|..|:...||
Human   274 FTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPA 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mps1	NP_001262677.1	PKc_Mps1	335..579	CDD:271033	42/179 (23%)
		S_TKc	337..575	CDD:214567	42/175 (24%)
TTBK2	XP_005254228.1	PKc_like	75..287	CDD:304357	49/207 (24%)
		SPS1	78..>267	CDD:223589	46/187 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3763
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950