Protein Alignment CG14325 and Nlrc3

DIOPT Version :10

• Sequence 1: NP_650641.2
• Gene: CG14325 / 42123
• FlyBaseID: FBgn0038531
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: XP_011244204.1
• Gene: Nlrc3 / 268857
• MGIID: 2444070
• Length: 1109
• Species: Mus musculus
• Alignment Length: 276
• Identity: 71/276 - (25%)
• Similarity: 116/276 - (42%)
• Gaps: 39/276 - (14%)

  Fly   163 DICAAYINQLEISFLQPAPPTTDANDHIPLDYLLSNLPDL---RQLRLSYS------TKTVG--- 215
            |||:               |..|.:..:....|.|.||.|   :.|||..:      .:.:|
Mouse   649 DICS---------------PEADFSLCLSQHVLQSLLPQLLYCQSLRLDNNQFQDPVMELLGSVL 698

  Fly   216 ----CNYQ---MGCNQLTVRDILHLTKGLSQCHELRTFCLHNTKLMPYQLRFLAHSLDKGCHHLT 273
                |..:   :..||:..:....|.:.|.....|.|..|.:..:.|...:.||.:| |....||
Mouse   699 SGKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADAL-KINRTLT 762

  Fly   274 EMSLLHCAVGDAGIRCFLETCGKESFGTLTVLDLTNNKITEEGAYILSRTLR-HVPLEKLVLRLN 337
            .:||....:.|.|:.|..|..  .|..|:::|.|..|.|...||..::..|: :..|:.|:...|
Mouse   763 SLSLQSNVIKDDGVMCVAEAL--VSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSN 825

  Fly   338 PIQSDGAAAIFNTLQVMPIKE-LDLGTCGITETITKLFMMLICQHTSLLEIDLSNNSLGEDFGKH 401
            .|...||.|:...|:|..|.| |||.:..|::....:.|..:|.:.:|..::|..||:..:..:.
Mouse   826 TIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQA 890

  Fly   402 LMKIISCNKLLERLDL 417
            |.:.:..|..|:.|||
Mouse   891 LTQALCRNNTLKHLDL 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14325	NP_650641.2	RNA1	<185..434	CDD:444072	67/254 (26%)
		leucine-rich repeat	202..239	CDD:275380	10/55 (18%)
		leucine-rich repeat	240..271	CDD:275380	8/30 (27%)
		leucine-rich repeat	272..301	CDD:275380	9/28 (32%)
		leucine-rich repeat	302..326	CDD:275380	7/24 (29%)
		leucine-rich repeat	329..353	CDD:275380	8/23 (35%)
		leucine-rich repeat	356..383	CDD:275380	8/27 (30%)
		leucine-rich repeat	384..407	CDD:275380	5/22 (23%)
Nlrc3	XP_011244204.1	NACHT	28..>776	CDD:444362	32/142 (23%)
		NACHT	176..342	CDD:428606
		RNA1	<665..952	CDD:444072	66/245 (27%)
		leucine-rich repeat	673..701	CDD:275380	5/27 (19%)
		leucine-rich repeat	705..730	CDD:275380	4/24 (17%)
		leucine-rich repeat	733..760	CDD:275380	8/27 (30%)
		leucine-rich repeat	761..788	CDD:275380	9/28 (32%)
		leucine-rich repeat	789..816	CDD:275380	7/26 (27%)
		leucine-rich repeat	817..840	CDD:275380	7/22 (32%)
		leucine-rich repeat	845..872	CDD:275380	7/26 (27%)
		leucine-rich repeat	873..900	CDD:275380	6/26 (23%)
		leucine-rich repeat	901..928	CDD:275380	4/6 (67%)
		leucine-rich repeat	929..949	CDD:275380
		LRR_6	954..976	CDD:463907
		leucine-rich repeat	957..977	CDD:275380
		leucine-rich repeat	985..1012	CDD:275380
		leucine-rich repeat	1013..1047	CDD:275380
		leucine-rich repeat	1048..1075	CDD:275380
		leucine-rich repeat	1076..1095	CDD:275380