DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sll and Slc35b2

DIOPT Version :9

Sequence 1:	NP_001247153.1	Gene:	sll / 42115	FlyBaseID:	FBgn0038524	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001344034.1	Gene:	Slc35b2 / 73836	MGIID:	1921086	Length:	431	Species:	Mus musculus

Alignment Length:	413	Identity:	194/413 - (46%)
Similarity:	269/413 - (65%)	Gaps:	23/413 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 WFLKLLVNCFGYSCVFVPGFLIYKYVGRINYLERGNKTFLHKAINMCITGN--SGYDQ--LDAGT 120
            |..:.|:|..||:...|||:|:.:|:.|.||||.| :......:..|:.||  ...|:  |...|
Mouse    35 WLFRFLLNVAGYASFMVPGYLLVQYLRRKNYLETG-RGLCFPLVKACVFGNEPKAPDEVLLAPRT 98

  Fly   121 STADKDRPAASTAPKRTSSQEAVQLLWCFGGLMISYLTWGVLQEKIMTQNY-LNFTGESAKFKDS 184
            .||:.           |.|.:.::|::|..||.:||||||:|||::||.:| ...|.....|.||
Mouse    99 ETAES-----------TPSWQVLKLVFCASGLQVSYLTWGILQERVMTGSYGATATSPGEHFTDS 152

  Fly   185 QFLVFSNRLLAFLVALAY--LQWQPSPVRHRAPLYKYSYASFSNIMSAWFQYEALKFVNFPTQVL 247
            ||||..||:||.:||..|  |:.||   ||.||:|:||:||.||::|:|.||||||||:||||||
Mouse   153 QFLVLMNRVLALVVAGLYCVLRKQP---RHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVL 214

  Fly   248 AKSCKIIPVMLMGKIMSKAKYESYEYVTALLISLGMIFFMSGSSDSSKASGVTTLTGIFLLSMYM 312
            ||:.|:||||:|||::|:..||.:||:||.|||:|:..|:..|....::|..|||:|:.||:.|:
Mouse   215 AKASKVIPVMMMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGPEPRSSPATTLSGLVLLAGYI 279

  Fly   313 VFDSFTANWQGSLFKSYGMTPLQMMCGVNLFSSIFTGASLSMQGGFMDSLAFATEHPKFVFDMVV 377
            .|||||:|||.:|| :|.|:.:|||.||||||.:||..||..||..::...|...|.:|....::
Mouse   280 AFDSFTSNWQDALF-AYKMSSVQMMFGVNLFSCLFTVGSLLEQGALLEGARFMGRHSEFALHALL 343

  Fly   378 LSVCSAVGQLFIYHTIDVFGPVVFTIIMTLRQAVAIMLSCFIYQHSISLLGIFGVLIVFVAIFLR 442
            ||:|||.|||||::||..||..|||||||||||:||:|||.:|.|:::::|..||.:||.|:.||
Mouse   344 LSICSAFGQLFIFYTIGQFGAAVFTIIMTLRQAIAILLSCLLYGHTVTVVGGLGVAVVFTALLLR 408

  Fly   443 VYCTQRLRAIRKRAEANKPKMAV 465
            ||...|.:..:|......|...|
Mouse   409 VYARGRKQRGKKAVPTEPPVQKV 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sll	NP_001247153.1	UAA	144..444	CDD:285625	162/302 (54%)
Slc35b2	NP_001344034.1	UAA	111..412	CDD:312076	164/304 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830788
Domainoid	1	1.000	326	1.000	Domainoid score	I1184
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H24504
Inparanoid	1	1.050	361	1.000	Inparanoid score	I2185
Isobase	1	0.950	-	0	Normalized mean entropy	S2363
OMA	1	1.010	-	-		QHG54403
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005467
OrthoInspector	1	1.000	-	-		oto92683
orthoMCL	1	0.900	-	-		OOG6_105624
Panther	1	1.100	-	-	LDO	PTHR10778
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R581
SonicParanoid	1	1.000	-	-		X3887
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.880