Protein Alignment sll and SLC35H1

DIOPT Version :10

• Sequence 1: NP_524389.1
• Gene: sll / 42115
• FlyBaseID: FBgn0038524
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_001268387.1
• Gene: SLC35H1 / 51006
• HGNCID: 17117
• Length: 394
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 76/382 - (19%)
• Similarity: 129/382 - (33%)
• Gaps: 88/382 - (23%)

  Fly   128 PAASTAP------------------KRTSSQEAVQLLWCFGGLMISYLTWGVLQEKIMTQNYLNF 174
            ||.|.||                  |...:...|.|.:||...:..|..|       :|::
Human    17 PADSGAPVLQPPRMGRWALDVAFLWKAVLTLGLVLLYYCFSIGITFYNKW-------LTKS---- 70

  Fly   175 TGESAKFKDSQFLVFSNRLLAFLV-ALAYLQWQPSPVRHRAPLYKYSY---------ASFSNI-M 228
                  |....|:...:..:.||. ||:....|.|..|.|..|....|         |:..:: :
Human    71 ------FHFPLFMTMLHLAVIFLFSALSRALVQCSSHRARVVLSWADYLRRVAPTALATALDVGL 129

  Fly   229 SAWFQYEALKFVNFPTQVLAKSCKIIPVMLMGKIMSKAKYESYEYVTALLISLGMIFFMSGSSDS 293
            |.|    :..:|......:.||..::.:::...|....:..:...:..|||:.|:..|...|:..
Human   130 SNW----SFLYVTVSLYTMTKSSAVLFILIFSLIFKLEELRAALVLVVLLIAGGLFMFTYKSTQF 190

  Fly   294 SKAS-----GVTTLTGIFLLSMYMVFDSFTANWQGSLFKSYGMTPLQMMCGVNLFSSIFTGASLS 353
            :...     |.:.:.||......|:........|..:...:.:.|| |..|:....::|.|..||
Human   191 NVEGFALVLGASFIGGIRWTLTQMLLQKAELGLQNPIDTMFHLQPL-MFLGLFPLFAVFEGLHLS 254

  Fly   354 MQGGFMDSLAFATEHPKFVFDMVVLSVCSAVGQLFIYHTIDVFG-------------PVVFTIIM 405
                        |....|.|....| :...:|.||: ..|..||             .:..:|..
Human   255 ------------TSEKIFRFQDTGL-LLRVLGSLFL-GGILAFGLGFSEFLLVSRTSSLTLSIAG 305

  Fly   406 TLRQAVAIMLSCFIYQHSISLLGIFGVLIVFVAIFLRVYCTQRLRAIRKRAEANKPK 462
            ..::...::|:..:....||||...|..:....|.|.|    .|:|:..|.:.. ||
Human   306 IFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHV----ALKALHSRGDGG-PK 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sll	NP_524389.1	UAA	144..444	CDD:462479	63/328 (19%)
SLC35H1	NP_001268387.1	TPT_S35C2	109..356	CDD:411044	50/270 (19%)