DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sll and SLC35B1

DIOPT Version :9

Sequence 1:	NP_001247153.1	Gene:	sll / 42115	FlyBaseID:	FBgn0038524	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_006721695.1	Gene:	SLC35B1 / 10237	HGNCID:	20798	Length:	393	Species:	Homo sapiens

Alignment Length:	369	Identity:	106/369 - (28%)
Similarity:	173/369 - (46%)	Gaps:	56/369 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 GNSGYDQLDAGTSTADKDRPAASTAPKRTSSQEAVQLLWCFGGLMISYLTWGVLQEKIM------ 167
            |:||  :|.|.:|:...||               ::|..||.|:.:.|..:|:||||:.
Human    32 GSSG--RLMASSSSLVPDR---------------LRLPLCFLGVFVCYFYYGILQEKMTRVGPLL 79

  Fly   168 -----------------TQNYLNFT-------GESAKFKDSQF---LVFSNRLLAFLVALAYLQW 205
                             ::|.::..       ||.||.:...|   |||...::..:.|...:|:
Human    80 VLPDACKQPIRPRPWCHSRNTVSSCLGTRGKYGEGAKQETFTFALTLVFIQCVINAVFAKILIQF 144

  Fly   206 QPSPVRHRAPLYKYSYASFSNIMSAWFQYEALKFVNFPTQVLAKSCKIIPVMLMGKIMSKAKYES 270
            ..:....|...:.|:..|.|.:.:......||:|||:|||||.||||.|||||:|..:.|.||..
Human   145 FDTARVDRTRSWLYAACSISYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPL 209

  Fly   271 YEYVTALLISLGMIFFMSGSSDSSKASGVTTLT---GIFLLSMYMVFDSFTANWQGSLFKSYGMT 332
            .:|:..|||..|:..||   ....|..|:...|   |..||.:.:..|..|...|..:...|...
Human   210 AKYLCVLLIVAGVALFM---YKPKKVVGIEEHTVGYGELLLLLSLTLDGLTGVSQDHMRAHYQTG 271

  Fly   333 PLQMMCGVNLFSSIFTGASLSMQGGFMDSLAFATEHPKFVFDMVVLSVCSAVGQLFIYHTIDVFG 397
            ...||..:||:|::..|..:...|...:.|:||..:|..::::::..:.||:||.||:.|:..||
Human   272 SNHMMLNINLWSTLLLGMGILFTGELWEFLSFAERYPAIIYNILLFGLTSALGQSFIFMTVVYFG 336

  Fly   398 PVVFTIIMTLRQAVAIMLSCFIYQHSISLLGIFGVLIVFVAIFL 441
            |:..:||.|.|:...|:.|..::.:.||.:...|.::||:.:.|
Human   337 PLTCSIITTTRKFFTILASVILFANPISPMQWVGTVLVFLGLGL 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sll	NP_001247153.1	UAA	144..444	CDD:285625	98/334 (29%)
SLC35B1	XP_006721695.1	UAA	53..380	CDD:312076	96/329 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54403
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R581
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850