Protein Alignment Hmx and nkx2.1

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_571851.1
• Gene: nkx2.1 / 81883
• ZFINID: ZDB-GENE-010404-1
• Length: 346
• Species: Danio rerio
• Alignment Length: 340
• Identity: 90/340 - (26%)
• Similarity: 120/340 - (35%)
• Gaps: 92/340 - (27%)

  Fly   349 SKSPSH----------HPLHPLY-------HPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQ 396
            |.||.|          .||...|       :.||:.....:|.|..|...||.|       ..|.
Zfish     2 SMSPKHTTPFSVSDILSPLEESYKKVSMEGNNLGAPLASYRQPQVTQAAMQQHH-------MGHN 59

  Fly   397 PTTPTSSSSSGGGSSLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHG 461
            .|.|.:...:..|.|...|.      :.|||...:..|.||     :....||..|.:.::|.:|
Zfish    60 GTVPAAYHMTAAGVSQLSHT------AMGGYCNGNLGNMSD-----LPAYQDGMRGSTTATSWYG 113

  Fly   462 DGNSKR---------------------------------------KKKTRTVFSRAQVFQLESTF 487
            .....|                                       ::|.|.:||:|||::||..|
Zfish   114 TNPDPRFSTISRFMGSSSGMNMGSMSTLSSLADVGKGMGPLTSTPRRKRRVLFSQAQVYELERRF 178

  Fly   488 DLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANM------ANMAHAAQRL 546
            ..::|||:.||..||:.:.||.|||||||||.|.|.|||...::....|      ......:.|.
Zfish   179 KQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKVSQQQMQQDNGSCQQQQQSPRR 243

  Fly   547 VRVPVLYHDGTTAGFVPPPP-----PHHHPMQYYAAARNTSPPRPPLSSLVXG-------VGCLA 599
            |.||||..||.........|     .|||.........|||.......|.. |       :|..|
Zfish   244 VAVPVLVKDGKPCQGSSHTPNTGVQNHHHQGGNVMFMTNTSLSMSQHQSQQVGSAGQSLDLGQHA 308

  Fly   600 TAPMSLLKPPNSMAH 614
            .:|.||......::|
Zfish   309 ASPPSLQTQVPGLSH 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	30/55 (55%)
nkx2.1	NP_571851.1	Homeodomain	160..216	CDD:459649	30/55 (55%)