Protein Alignment Hmx and Hhex

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_077361.1
• Gene: Hhex / 79237
• RGDID: 619932
• Length: 271
• Species: Rattus norvegicus
• Alignment Length: 274
• Identity: 66/274 - (24%)
• Similarity: 93/274 - (33%)
• Gaps: 88/274 - (32%)

  Fly   260 QLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPGWP-WAPQRLPFHSPTH-------DSS 316
            |.|.||.                         ||....|.| :||  .|...|.|       |..
  Rat     2 QFPHPGP-------------------------AAAPAVGVPLYAP--TPLLQPAHPTPFYIDDIL 39

  Fly   317 STNTTENPPSPTSMSPNNNNNNSNTTASSNQASKSPSHHPLHPLYHPLGSQQQQQQQQQHQQHPQ 381
            ........|:||..||    |:|.|:..|:..:......|:||.:
  Rat    40 GRGPAAPTPTPTLPSP----NSSFTSLVSSYRTPVYEPTPVHPAF-------------------- 80

  Fly   382 QQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEE 446
                        .|.|....:::...||.....:|.|.....:...||     ..|..|:.::
  Rat    81 ------------SHHPAAALAAAYGPGGFGGPLYPFPRTVNDYTHALL-----RHDPLGKPLL-- 126

  Fly   447 DDGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQ 511
                      .:|.......::|..:..||..|..:||..|:.::|||..||..||..|:|:|.|
  Rat   127 ----------WNPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQ 181

  Fly   512 VKIWFQNRRNKWKR 525
            ||.||||||.||:|
  Rat   182 VKTWFQNRRAKWRR 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	28/55 (51%)
Hhex	NP_077361.1	Homeodomain	137..195	CDD:459649	28/57 (49%)