Protein Alignment Hmx and LOC4576841

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_001230938.4
• Gene: LOC4576841 / 4576841
• VectorBaseID: AGAMI1_003921
• Length: 540
• Species: Anopheles gambiae
• Alignment Length: 630
• Identity: 149/630 - (23%)
• Similarity: 232/630 - (36%)
• Gaps: 189/630 - (30%)

  Fly    23 AAARDSPLLARSPARSADGSSPPATPTHRSNTPNTAAGTPTTSASGGNHFHHSPSGGAVPPAVLH 87
            |..|...:|.|:       |||| .|.........:.|:|:....|....|         ||
Mosquito     5 ADLRSGKMLCRT-------SSPP-PPCSSPAGSEISVGSPSPPPIGSESAH---------PA--- 49

  Fly    88 HHLQHHLSSLGSHPVALHHALHTFGHLHPAHGATHPALLQ-HALTPTGQQQQQQL-----QVQQQ 146
             ||.|      .||:|:.|.:|....:|| |...|||.|. ||.....|.:.:..     :::..
Mosquito    50 -HLPH------PHPLAVTHLVHHHPLVHP-HHPHHPAALHAHAAVSALQARAEDYFTPLKRLRMV 106

  Fly   147 HQQSHVERLSPPMKSPERNGGDEVQGHSLNNNNSKALNHNNTCASAAAAAAAAAVAAANLSNNSN 211
            ...|.||..|||..||:.:........:..|:.|.|    ||..|...:..:|.....:.:.:||
Mosquito   107 EGGSGVELASPPGGSPKESTSRGSSPTTPINSASSA----NTVTSPNNSGNSATTLTTSTTTSSN 167

  Fly   212 DSNGSSGGGGGKSTTGSNGFTSFSISSILSR-SEPAKKNGAAGLITPIPQLPQPGAGGPQDAAML 275
            .:..|||      :|.:.|..||||:.||.| :|.|.:.||.          :|.
Mosquito   168 TTKPSSG------STAAEGVKSFSIADILGRDAEAASREGAR----------EPS---------- 206

  Fly   276 SRLGFISQWGALAGRYAALCPPGWPWAPQRLPFHSPTHDSSSTN-----TTENPPSPTSMSPNNN 335
                                ||         |.:...|.:|.::     |..:|.:..:.:.:::
Mosquito   207 --------------------PP---------PINPALHHASLSHHHLHLTGHHPAAHLAAAHHHH 242

  Fly   336 NNNSNTTASSNQASK--SPSHH-----PLHPLY--------HPLGSQQQQQQQQQHQQHPQQQQH 385
            :::.:::.....|||  .|..|     |:.|..        |.|.....||.|:..:...|..:|
Mosquito   243 HHHHSSSTLQQAASKIVRPWDHLRGPIPVRPFLPPALLHYEHRLALDYHQQLQEHFRAQAQLLRH 307

  Fly   386 ------PQQQQQQH-----------------PHQPTTPTSSSSSG-GGSSLTHHPHPHLTGSHGG 426
                  |.:...:.                 .||....:.||||| ||.|.........:|::||
Mosquito   308 MSMDIIPSESGSERSSSAASDCCSPEIGRGSDHQSHQSSQSSSSGVGGGSAGAGDGSGRSGANGG 372

  Fly   427 -------------------YLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPH-----GDGNSKR 467
                               .|...::...||..|             ||...|     .....|:
Mosquito   373 ASGAAKSGSKTAPNGTPLDALFQMTNKNFDESNE-------------DSEQSHLNLFANRPQPKK 424

  Fly   468 KKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKR---QLAA 529
            |:|:||.|:..|:|:||..|..::|||.|:|..:||:|.|:..||..||||||.|.||   :|..
Mosquito   425 KRKSRTAFTNHQIFELEKRFLYQKYLSPSDRDEIAAALGLSNAQVITWFQNRRAKLKRDMEELKK 489

  Fly   530 ELEAANMANMAHAA-------QRLVRVPVLYHDG---TTAGFVPP 564
            ::|...:.: ||..       ..:::..:::.||   ..|.|:.|
Mosquito   490 DVETVKVLS-AHKTFLENVNDMNILKKKIMHDDGGSPQNASFLHP 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	27/55 (49%)
LOC4576841	XP_001230938.4	None