Protein Alignment Hmx and NK7.1

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Alignment Length: 769
• Identity: 163/769 - (21%)
• Similarity: 259/769 - (33%)
• Gaps: 248/769 - (32%)

  Fly   113 HLHPAHGATHPALLQHALTPTGQQQQQQLQVQQQH--QQSHVERLSPPMKSPERNGGDEVQGHSL 175
            ||..|..|:  ..|.|.......|||||.|.||.|  ||.|..:.....:..:::..|..:....
  Fly    10 HLEAAEMAS--GALAHNYGIVKDQQQQQQQQQQLHHLQQQHHHQQQQQQQQQQQSNSDLYKMACN 72

  Fly   176 NNNNSKALNHNNT-----CASAAAAAAAAAVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTSFS 235
            ..|.|..|....|     ..|....:....|....:.:|:|
  Fly    73 GYNYSSPLTIPPTSMTTHMVSPIGNSKEKLVNMLRVRDNNN------------------------ 113

  Fly   236 ISSILSRSEPAK--KNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPG 298
            ::|.:|.|.|..  :.....::.|.|....|....||...:.     :.|........|....||
  Fly   114 MASTISDSPPTTFLQKQLEAVVAPRPSSVHPQHQQPQQQTVQ-----LQQQRRSVSTPAITTTPG 173

  Fly   299 WP--W---APQRLPFHSPTHD------------------------SSSTNTTENP--------PS 326
            .|  |   ...|||.|...|.                        :.|.|:...|        .|
  Fly   174 PPTNWHAHVYDRLPPHPTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSS 238

  Fly   327 PTSMSPNNNNNNSNTTASSNQAS--------------KSPSHHPLHPLY---------HPLGSQQ 368
            ..|||..:...::....:::.|:              .:|...||:...         .|:.:.:
  Fly   239 SISMSDASEEESAAVAGATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATK 303

  Fly   369 QQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHP----HPHLTGSHGGYLL 429
            |.|...:.....:....|..::::.......|...|.:|...||....    :....||:....:
  Fly   304 QSQILGKSATKKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQM 368

  Fly   430 PSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLS 494
            .|::|.:.|     ..|||...|.:|         ::||||.||.|:..|:|:||..|:.|:|||
  Fly   369 QSNANSTLE-----TTEDDSDSGSTD---------ARRKKKARTTFTGRQIFELEKMFENKKYLS 419

  Fly   495 SSERAGLAASLRLTETQVKIWFQNRRNKWKRQ------LAAELEAAN------------------ 535
            :|||..:|..|.:|||||||||||||.|||:|      .|||.:::|
  Fly   420 ASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKSSNAKPGATGTATTTPSGEPT 484

  Fly   536 -----------MANMAHAAQRLVRVPVLYHDGT--------------TAGFVPPPPPHHHPMQYY 575
                       :.|.|..|: :.:.|...:.|:              :.|.||
  Fly   485 DKRSSNATSPTVGNAATIAE-IKKSPKSPNRGSNNNNNNTLNNNVNNSEGKVP------------ 536

  Fly   576 AAARNTSPPRPPLSSLVXGVGCLATA---------------PMSLLKPPNS----MAH------- 614
             |.::|:..:..|::|:...  :.||               |....:|.||    :.|
  Fly   537 -AKQSTTKIKKQLNALLEKT--VKTANQAHRSAELESSDQKPAVEKRPNNSNENQLLHQRLHQHA 598

  Fly   615 -PPHPQPPPP-------------APLHMQ-----QRSFLGCEQLTETDMDS-------------- 646
             |...:|..|             :|.|.:     ||:.:...||||.|.:|
  Fly   599 IPLTVEPAAPLEQTEKLDIKREESPQHRELQLSLQRAAIQNGQLTEMDFESKLAASKISIALAMA 663

  Fly   647 DSEQERSHMMDDEDAAIDVEAD---EEQESASPVPSATPPKSSLCLESKESGGQ 697
            :.:.:....:..|.::.:.|.|   ||:|....|.|:....|   :|:.:|..|
  Fly   664 NKQMQPEKRVKTESSSSEGEGDGDGEEEEEEEEVSSSEHGDS---IEAHDSQDQ 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	34/55 (62%)
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	34/55 (62%)