Protein Alignment Hmx and ems

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 125/557 - (22%)
• Similarity: 183/557 - (32%)
• Gaps: 167/557 - (29%)

  Fly    18 PSPLGAAARDSPL-----------LARSPARSADGSS------PPATPTHRSNTPNTAAGTP--T 63
            |.|..|||...|.           :..:...:|.|:|      |.:.|....|.|.:...||  |
  Fly     7 PVPTAAAAVMMPTPKQKIGFSIESIVGNDVSTAGGNSTPDLSGPQSPPPGERNVPGSPPQTPPAT 71

  Fly    64 TSASGGNHFHH---SPSGGAVPPAVLHHHL-QHHLSSLGSHPVALHHALHTFGHLHPA-HGATHP 123
            .:...|:..||   .|:.|...|   |.|. |.||.:...||           ||.|| ....|.
  Fly    72 LTLIPGSPPHHLMAPPAHGLPYP---HPHAQQQHLQAPHPHP-----------HLSPAQQHVLHQ 122

  Fly   124 ALL---QHALTPTGQQQQQQLQVQQQHQQSHV--------ERLSPPMKSPERNGGDEVQGHSLNN 177
            .||   ||..||...|..|:| :|:.|..:.:        .||||..:.|:       ...||..
  Fly   123 HLLMQQQHPGTPKSHQDIQEL-LQRLHHNAAMASGLSPLQTRLSPETEQPQ-------MAVSLKR 179

  Fly   178 NNSKALNHNNTCASAAAAAAAAAVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTSFSISSILSR 242
            ..|.|........:.|...........::|..|:..:.|               .:..||| ...
  Fly   180 ERSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSS---------------PTLLISS-PHA 228

  Fly   243 SEPAKKNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCP--PGWPWAPQR 305
            :.|.::........|.|.:..||..||.....:...|.:..:           |  ||.|..||.
  Fly   229 TPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPF-----------PMGPGGPPMPQG 282

  Fly   306 LPFHSPTHDSSSTNTTENPP---SPTSMSPNNNNNNSNTTASSNQASKSPSHHPLHPLYHPLGSQ 367
            .|        ...:....||   :|..:.| .:|.:....|....|:...:.|.|.|......:.
  Fly   283 QP--------GLPDIKALPPYINAPPELPP-QHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAA 338

  Fly   368 QQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSH-------- 424
            .......|...:|                           |.:..::..:|.|...|
  Fly   339 GLPPHAAQFMPNP---------------------------GMARDSYQLYPWLLSRHGRIFPHRF 376

  Fly   425 -GGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFD 488
             |.:|:|.                                 .::.|:.||.||.:|:.:||..|:
  Fly   377 PGSFLVPP---------------------------------FRKPKRIRTAFSPSQLLKLEHAFE 408

  Fly   489 LKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKR 525
            ..:|:..:||..||.:|.|:|||||:||||||.|.||
  Fly   409 SNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKR 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	28/55 (51%)
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	28/55 (51%)