Protein Alignment Hmx and pb

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 121/607 - (19%)
• Similarity: 192/607 - (31%)
• Gaps: 235/607 - (38%)

  Fly   136 QQQQQLQVQQQHQQSHVERLSPPMKSPERNGGDEVQG---HSLNNNNSK---------------- 181
            ::|.::..|.:..:...:.||   |:.:.:..|.::|   .|.:|:|||
  Fly   239 ERQVKVWFQNRRMKHKRQTLS---KTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDS 300

  Fly   182 ---ALNHNNTCASAAAAAAAAAVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTS--FSISSILS 241
               :..|||...||.....    :|.||:.||:...|.|....|.:|..::...|  .|::|.:|
  Fly   301 TSNSRGHNNNTPSATNNNP----SAGNLTPNSSLETGISSNLMGSTTVSASNVISADSSVASSVS 361

  Fly   242 RSEPAKKNGAAGLITPIP-QLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPGWP-WAPQ 304
            ..|..:::      :||. :....|....::|...|               :...|.|:. ..|.
  Fly   362 LDEDIEES------SPIKVKKKDDGQVIKKEAVSTS---------------SKASPFGYENSTPS 405

  Fly   305 RLPFHSPTHDSSSTNTTENPPS-----------------PTSMSPNNNNNNSNTTASSNQASKSP 352
            .:.|.   .||.::.....|.|                 ||.:|.:|:.|.|....:..
  Fly   406 LVSFR---RDSDASAVGNAPTSKAVGKKRFQSAANAIATPTPLSDSNSGNGSGGGPAGG------ 461

  Fly   353 SHHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQH-----------PHQPTTPTSSSSS 406
                ..|.|:|  |.:||||.||.|.||||||.||||.|.:           ||
  Fly   462 ----YFPGYYP--SPKQQQQVQQQQLHPQQQQLPQQQPQDYYGKYDIEFAASPH----------- 509

  Fly   407 GGGSSLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEEDD----------GT----------- 450
                   |:||......||.||.|..|:.:..:..:..:::|          ||
  Fly   510 -------HNPHNKQQALHGEYLSPKPSSANFHQNSQQQQQNDHFYYNYNDTNGTPYLNHQQQHHH 567

  Fly   451 ------------------DGPSDSSSPHGDG----NSKRKKKTRTVFSRAQVFQLES-------T 486
                              :||.:..|...:|    |...:::.:....:..|||.:.       .
  Fly   568 HAQHHQQQQHHQNHVADFEGPVNGPSNFNNGAYYDNMSFQQQAQAHQHQTVVFQQQQPHQPAAIN 632

  Fly   487 FDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANMANMAHAAQRLVRVPV 551
            .....:|.:.|...                         .|..::|.....|...||
  Fly   633 HQHMHHLGNGETYS-------------------------ALGLQMENCEGYNNFGAA-------- 664

  Fly   552 LYHDGTTAGFV-----PP-PPPH---HHPMQYYAAARNTSPPRPPLSS--LVXGVGCLATAPMSL 605
                ||..|:.     || |..|   |||......|:..:|.....:|  :. |||.
  Fly   665 ----GTGGGYYEAGQQPPIPATHGHGHHPHHVQVPAQAHAPIHAHHNSAAIPGGVGV-------- 717

  Fly   606 LKPPNSMAHPPHPQPPPPAPLH 627
                          .|||:.:|
  Fly   718 --------------GPPPSHIH 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	5/62 (8%)
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	2/15 (13%)