Protein Alignment Hmx and Dbx

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 658
• Identity: 143/658 - (21%)
• Similarity: 196/658 - (29%)
• Gaps: 290/658 - (44%)

  Fly    70 NHFHHSPSGGAVPPAVLHHHLQHHLSSLGSHPVALHHALHTFGHLHPAHGAT---HPALLQHALT 131
            :|..|.|.  |||.   |.|         |||.:.||  |   |.||..|..   |||.|.|.|
  Fly   207 SHPQHQPL--AVPG---HQH---------SHPHSHHH--H---HHHPGAGHAHFPHPAFLTHQL- 251

  Fly   132 PTGQQQQQQLQVQQQHQQSHVERLSPPMKSPERNGGDEVQGHSLNNNNSKALNHNNTCASAAAAA 196
            |..|..|||..|||||.                                     .|:|....|::
  Fly   252 PPHQHHQQQQHVQQQHP-------------------------------------GNSCQPQTASS 279

  Fly   197 AAAAVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTSFSISSILSRSEPAKKNGAAGLITPIPQL 261
            :::..:..:.|:|::.::.::|.|.|   ||::|
  Fly   280 SSSPGSTISDSDNNHGASTANGNGSG---TGNSG------------------------------- 310

  Fly   262 PQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPGWPWAPQRLPFHSPTHDSSSTNTTENPPS 326
                    |||                             .|..|...:|..|||::...
  Fly   311 --------QDA-----------------------------RPHELANSNPDEDSSASRRL----- 333

  Fly   327 PTSMSPNNNNNNSNTTASSNQASKSPSHHPLHPLYHPLGSQQQQQQQQ--------------QHQ 377
                                                   :|.:|||||              ...
  Fly   334 ---------------------------------------TQDKQQQQQLLGAGGTGGGGGGGHGH 359

  Fly   378 QHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTH---HPHPHLTGSHGGYLLPSSSNESDEE 439
            .||.....|.......| .|:.||        ..|.|   |||.|       .||....|.....
  Fly   360 GHPTPPPPPPPPVIAKP-MPSRPT--------PFLPHTLNHPHLH-------SLLAHCRNPYMSV 408

  Fly   440 GEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAAS 504
            |.::.....|...|...|:   .|..:|....|.|||.:|...||..|..::|:|..:|..||..
  Fly   409 GAQVFPLPPGQGFPWAHST---RGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAER 470

  Fly   505 LRLTETQVKIWFQNRRNKWKRQLAAELEAANMANMAHAAQRLVRVPVLYHDGTTAGFVPPPPPHH 569
            |.|.::||||||||||.||:.....||       :|....|...:|
  Fly   471 LGLKDSQVKIWFQNRRMKWRNSKEREL-------LASGGSRDQTLP------------------- 509

  Fly   570 HPMQYYAAARNTSPPRPPLSSLVXGVGCLATAPMSLLKP----PNSMAHPPHP------QPP--- 621
                      |.:.|.|.||.      .....|::.|.|    ||..|.||.|      :||
  Fly   510 ----------NKNNPNPDLSD------AKCDRPLTPLSPSLLSPNGSATPPPPGAVAKDEPPTAA 558

  Fly   622 --PPAPLHMQQRSFLGCEQLTETDMDSDSEQERSHMMDDEDAAIDVEADEEQESASPVP------ 678
              |.:|..:..||             |.|......:.........::..::..||:|.|
  Fly   559 VTPKSPQSVSSRS-------------SPSVGYGLQISSPPPLLTSLKMGDQSASATPTPLPGTTV 610

  Fly   679 ---SATPP 683
               :|:||
  Fly   611 SSAAASPP 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	27/55 (49%)
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	27/53 (51%)