Protein Alignment Hmx and Gsx2

DIOPT Version :10

• Sequence 1: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001131035.2
• Gene: Gsx2 / 364140
• RGDID: 1308047
• Length: 305
• Species: Rattus norvegicus
• Alignment Length: 326
• Identity: 82/326 - (25%)
• Similarity: 114/326 - (34%)
• Gaps: 93/326 - (28%)

  Fly   230 GFTSFSISSILSRSEPAKKNGAAGLITPI-------PQLPQPGAGGPQDAAMLSRLGFISQWGAL 287
            |..|..:.|:.....|::|:||. .:.|:       ...|..||||    ......|.....|.:
  Rat    36 GMPSPLVMSVSGPGCPSRKSGAF-CVCPLCVTSHLHSSRPPAGAGG----GATGTAGAAVAGGGV 95

  Fly   288 AGRYAALCPPGWPWAPQRLPFHSPTHDSSSTNTTENPPSPTSMSPNNNNNNSNTTASSNQASKSP 352
            ||...||        |......||            .|......|.                .|.
  Rat    96 AGGTGAL--------PLLKSQFSP------------GPGDAQFCPR----------------VSH 124

  Fly   353 SHHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPH 417
            :||                    |...||...|..|.||..........:::::...::|.|..|
  Rat   125 AHH--------------------HHHAPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAAALGHPQH 169

  Fly   418 PHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSS-PHGDGNSKRKKKTRTVFSRAQVF 481
                  |......::.|.||......:     |.|.||:|. |:|       |:.||.|:..|:.
  Rat   170 ------HAPVCAATTYNVSDPRRFHCL-----TMGGSDTSQVPNG-------KRMRTAFTSTQLL 216

  Fly   482 QLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANMANMAHAAQRL 546
            :||..|....|||...|..:|..|.|:|.||||||||||.|.|:    |.:.|:..|  ||:.:.
  Rat   217 ELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKK----EGKGASRNN--HASCKC 275

  Fly   547 V 547
            |
  Rat   276 V 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	27/55 (49%)
Gsx2	NP_001131035.2	Homeodomain	204..260	CDD:459649	27/55 (49%)